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Old 09-15-2008, 08:06 AM   #1
Becky
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How Much Omega 3 Capsules Are Right?

I know one should specifically do the math to balance the Omega 6 and 3 but in general, how many capsules should be taken per day.

Dean Ornish says 8 per day unless you are eating a big hunk of salmon for dinner.

What is a generic right amount?

RB - any suggestions?
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Kind regards

Becky

Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia

NED 18 years!

Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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Old 09-15-2008, 08:36 AM   #2
SoCalGal
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Hi Becky-
I started by taking (2) capsules of ULTIMATE OMEGA by Nordic Naturals (1000 mg) daily. (I now take 3 due to some heart stuff and after 3 mos on 3 a day I have had no more episodes of heart stuff.) I also take an E- liquid D- a multi - vit C - calcium - etc. etc.

Because I eat no gluten (wheat) or dairy I really don't get much Omega 6 at all. The red meat I eat is grass fed organic. The lamb is grass fed new zealand. And I only buy omega enriched eggs. I do eat salmon at least 3 times a week if not more often.

Plus my Starbucks
Regards!
Flori
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1996 cancer WTF?! 1.3 cm lumpectomy Er/Pr neg. Her2+ (20nodes NEGATIVE) did CMF + rads. NED.
2002 recurrence. Bilateral mastectomy w/TFL autologous recon. Then ACx2. Skin lymphatic rash. Taxotere w/Herceptin x4. Herceptin/Xeloda. Finally stops spreading.
2003 - Back to surgery, remove skin mets, and will have surgery one week later when pathology can confirm margins.
‘03 latisimus dorsi flap to remove skin mets. CLEAN MARGINS. Continue single agent Herceptin thru 4/04. NED.
‘04 '05 & 06 tiny recurrences - scar line. surgery to cut out. NED each time.
1/2006 Rads again, to scar line. NED.

3/07 Heartbreaking news - mets! lungs.sternum. Try Tykerb/Xeloda. Tykerb/Carbo/Gemzar. Switch Oncs.
12/07 Herceptin.Tykerb. Markers go stable.
2/8/08 gamma knife 13mm stupid brain met.
3/08 Herceptin/tykerb/avastin/zometa.
3/09 brain NED. Lungs STABLE.
4/09 attack sternum (10 daysPHOTONS.5 days ELECTRONS)
9/09 MARKERS normal!
3/10 PET/CT=manubrium intensely metabolically active but stable. NEDhead.
Wash out 5/10 for tdm1 but 6/10 CT STABLE, PET improving. Markers normal. Brain NED. Resume just Herceptin plus ZOMETA
Dec 2010 Brain NED, lungs/sternum stable. markers normal.
MAR 2011 stop Herceptin/allergy! Go back on Tykerb and switch to Xgeva.
May-Aug 2011 Tykerb Herceptin Xgeva.
Sept 2011 Tykerb, Herceptin, Zometa, Avastin.
April 2012 sketchy drug trial in NYC. 6 weeks later I’m NED!
OCT 2012 PET/CT shows a bunch of freakin’ progression. Back to LA and Herceptin.avastin.zometa.
12/20/12 add in PERJETA!
March 2013 – 5 YEARS POST continue HAPZ
APRIL 2013 - 6 yrs stage 4. "FAILED" PETscan on 4/2/13
May 2013: rePetted - improvement in lungs, left adrenal stable, right 6th rib inactive, (must be PERJETA avastin) sternum and L1 fruckin'worsen. Drop zometa. ADD Xgeva. Doc says get rads consultant for L1 and possible biopsy of L1. I say, no thanks, doc. Lets see what xgeva brings to the table first. It's summer.
June-August 2013HAPX Herceptin Avastin Perjeta xgeva.
Sept - now - on chemo hold for calming tummy we hope. Markers stable for 2 months.
Nov 2013 - Herceptin-Perjeta-Avastin-Xgeva (collageneous colitis, which explains tummy probs, added Entocort)
December '13 BRAIN MRI ned in da head.
Jan 2014: CONTINUING on HAPX…
FEB 2014 PetCT clinical “impression”: 1. newbie nodule - SUV 1.5 right apical nodule, mildly hypermetabolic “suggestive” of worsening neoplastic lesion. 2. moderate worsening of the sternum – SUV 5.6 from 3.8
3. increasing sclerosis & decreasing activity of L1 met “suggests” mild healing. (SUV 9.4 v 12.1 in May ‘13)
4. scattered lung nodules, up to 5mm in size = stable, no increased activity
5. other small scattered sclerotic lesions, one in right iliac and one in thoracic vertebral body similar in appearance to L1 without PET activity and not clearly pathologic
APRIL 2014 - 6 YRS POST GAMMA ZAP, 7 YRS MBC & 18 YEARS FROM ORIGINAL DX!
October 2014: hold avastin, continue HPX
Feb 2015 Cancer you lost. NEDHEAD 7 years post gamma zap miracle, 8 years ST4, +19 yrs original diagnosis.
Continue HPX. Adding back Avastin
Nov 2015 pet/ct is mixed result. L1 SUV is worse. Continue Herceptin/avastin/xgeva. Might revisit Perjeta for L1. Meantime going for rads consult for L1
December 2015 - brain stable. Continue Herceptin, Perjeta, Avastin and xgeva.
Jan 2016: 5 days, 20 grays, Rads to L1 and continue on HAPX. I’m trying to "save" TDM1 for next line. Hope the rads work to quiet L1. Sciatic pain extraordinaire :((
Markers drop post rads.
2/24/16 HAP plus X - markers are down
SCIATIC PAIN DEAL BREAKER.
3/23/16 Laminectomy w/coflex implant L4/5. NO MORE SCIATIC PAIN!!! Healing.
APRIL 2016 - 9 YRS MBC
July 2016 - continue HAP plus Xgeva.
DEC 2016 - PETCT: mets to sternum, lungs, L1 still about the same in size and PET activity. Markers not bad. Not making changes if I don't need to. Herceptin/Perjeta/Avastin/Xgeva
APRIL 2017 10 YEARS MBC
December 2017 - Progression - gonna switch it up
FEB 2018 - Kadcyla 3 cycles ---->progression :(
MAY30th - bronchoscopy, w/foundation1 - her2 enriched
Aug 27, 2018 - start clinical trial ZW25
JAN 2019 - ZW25 seems to be keeping me stable
APRIL 2019 - ONE DOZEN YEARS LIVING METASTATIC
MAY 2019 - progression back on herceptin add xeloda
JUNE 2019 - "6 mos average survival" LMD & CNS new single brain met - one zap during 5 days true beam SBRT to cord met
10/30/19 - stable brain and cord. progression lungs and bones. washing out. applying for ds8201a w nivolumab. hope they take me.
12/27/19 - begin ds8401a w nivolumab. after 2nd cycle nodes melt away. after 3rd cycle chest scan shows Improvement, brain MRI shows improvement, resolved areas & nothing new. switch to plain ENHERTU. after 4th cycle, PETscan shows mostly resolved or improved results. Markers near normal. I'm stunned but grateful.
10/26/20 - June 2021 Tucatinib/xeloda/herceptin - stable ish.
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Old 09-16-2008, 02:17 PM   #3
R.B.
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Hi

I posted some of this on another thread but it applies equally here.

HOW MUCH EPA AND DHA.

There are no absolute answers. Flori is taking about 1.5 grams of EPA and DHA a day which is about the maximum that is accepted as not posing any serious risk for most people.

There is a trial that shows the uptake in women dropping off at about 2 grams of DHA a day so 1.5grams is getting towards what may be the maximum.

If you have digestive problems then the Omega 3 may not be being digested which is an argument for not taking say 200mg a day.

But talk to your doctor and do not take this level of fish oil / DHA EPA before that if you are on blood thinners medication etc.

VEGETARIAN OR BLOCKED CONVERSION

You cannot assume that you are able to convert the plant omega 3s to DHA and EPA. Lots of things can block that pathway. Loss of oestrogen function results in the conversion ability dropping significantly.

There are sources of EPA and DHA for vegetarians (although algae are strictly living in a sense).


TUNA - The longer liver the fish the greater the amount of contaminants including mercury. There are concerns about tuna consumption with varying recommendations as to the maximum to eat a week from 1 - 3 portions.

http://www.consumerreports.org/cro/b...07_tuna_ov.htm

Small oily fish are better and have more long chain Omega 3s - Atlantic mackerel, sardines etc.

REDUCE OMEGA 6 INTAKE.

Many trials suggest higher Omega 6 contributes to the risk of BC. http://her2support.org/vbulletin/showthread.php?t=24410


We only need about 1% - 2% of calories of the plant based Omega Six, and some suggest the figure is as low as 1/2%. ISSFAL the International Society for the Study of Fatty Acids and Lipids suggests a maximum of 3%.

Most have an intake of 10% or above.

For me that needs to be balanced with the plant based Omega 3 on the basis that there is generally more Omega 3 than 6 in green things which is where the food chain starts.

Seasonally we we have got some seeds and nuts which are high in Omega 6 which would have pushed the balance back towards Omega 6.

If evolved by the shore by accident or design we would always have had access to marine foods which are generally much higher in long chain Omega 3s than 6, which is why it is fine to get more long chain 3 than 6 ( as well as being shown to be beneficial in lots of trials for a variety of illnesses)

FLAXSEED

Flax seed may be of benefit, but a subject of much discussion so please talk to your onc and show him or her the trial.

Here is a trial link
http://clincancerres.aacrjournals.or...ull/11/10/3828

"Our study is small and the results need to be confirmed in a larger number of patients for a longer treatment period before it can be definitively concluded that flaxseed has the potential to reduce the growth and invasiveness of breast cancer. Its excellent tolerability, however, may make flaxseed particularly attractive for studies in breast cancer prevention, where healthy women should be offered well-tolerated interventions for long-term use. The interaction of flaxseed and its lignan and oil components with other hormonally active agents also needs to be addressed in the future. If the therapeutic index seen in this short-term study can be sustained over a long-term period, flaxseed, which is inexpensive and readily available, may be a potential dietary alternative or adjunct to currently used breast cancer drugs."


FLAXSEED AND IODINE.

Flaxseed blocks iodine uptake to a certain extent, so please make sure you are getting adequate iodine.


MINERALS

Mineral are important to the processing of fats. So please make sure you get adequate minerals to. Fish and shell fish are good sources of various minerals, which you will not get in oil.

Last edited by R.B.; 09-16-2008 at 03:32 PM..
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