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Old 10-25-2009, 07:27 PM   #1
Cal-Gal
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Location: Los Angeles, CA
Posts: 309
What is the difference between PET/CT/Bone Scan

Hi there--

Can someone explain the difference --
or actually what shows and what doesn't in these different tests:

  • PET
  • CT
  • Bone Scans

I had a PET and a CT right aft my surgery and subsequently 2 more CT scans--have not had a bone scan--

Thanks---
__________________
DX: 11/08 Age: 53
Surgery: 1/09
Bilat Mastectomy, no reconstruction
ILC-4 tumors-1.7 cm,1.5 cm (2).8 cm
DCIS-11 cm
All tumors Grade 3
All tumors ER-0%/PR-0%
All tumors HER2+
IHC-all tumors Overexpression/borderline
FISH 2 tumors Her2-Negative
FISH 2 tumors Her2+ Equivocal
Stage I, 0/1 nodes
LVI-Indeterminate(treated as positive)
SPR Score 8/9
Ki-67 20%
BRCA genetic test 1/2=negative
Chemo: 6 rounds TAC Feb-June 2009 w/Neulasta
Herceptin: 6/12/09-6/4/10 52weeks
HNPCC genetic test: negative
Port Placement-9/23/09 Port Removal 6/25/10
Echo's every 3 months-All normal
2/09 Staging PET/CT showed 0.2 micronodule upper R lobe-lung-Onc does not think this is mets--
6/5/09 AND 10/09 CT scan 0.2 micronodule unchanged
1/10-PET/CT-uptake in nasopharynx-
1/10-MRI All normal
6/10-Bone Scan-clear
12/10-PET/CT-All Clear-NED
12/11-PET-All Clear-NED

12/12-PET-All Clear-NED
12/13-CT w/contrast Head, Torso-All Clear
12/14-CT w/contrast Head-All Clear
2/15-Core needle biopsy-R scar line

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Old 10-25-2009, 07:39 PM   #2
Rich66
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Location: South East Wisconsin
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Re: What is the difference between PET/CT/Bone Scan

PET shows areas of metabolic activity (sugar uptake), usually of cancer cells. judged as to whether an area "lights up".

CT gives a "picture" of masses, good for tracking size of tumor. Often done with contrast injection to give clearer image.
PET and CT are sometimes done separately and matched up, whereas sometimes done together on the same PET/CT machine. PET is thought to show changes in cancer before it is visible on CT.

Cancer bone scan shows bone metastases activity. Not to be confused with bone density scan for osteoporosis.
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Old 10-25-2009, 07:45 PM   #3
Cal-Gal
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Re: What is the difference between PET/CT/Bone Scan

Thanks Rich-

I had the combo PET/CT scan in January and the CT w/dye the last 2 times-

Thanks for clarification on bone scans--I have never had one--and didnt know if that is an area or possibly area of concern that is covered in the CT or PET--
__________________
DX: 11/08 Age: 53
Surgery: 1/09
Bilat Mastectomy, no reconstruction
ILC-4 tumors-1.7 cm,1.5 cm (2).8 cm
DCIS-11 cm
All tumors Grade 3
All tumors ER-0%/PR-0%
All tumors HER2+
IHC-all tumors Overexpression/borderline
FISH 2 tumors Her2-Negative
FISH 2 tumors Her2+ Equivocal
Stage I, 0/1 nodes
LVI-Indeterminate(treated as positive)
SPR Score 8/9
Ki-67 20%
BRCA genetic test 1/2=negative
Chemo: 6 rounds TAC Feb-June 2009 w/Neulasta
Herceptin: 6/12/09-6/4/10 52weeks
HNPCC genetic test: negative
Port Placement-9/23/09 Port Removal 6/25/10
Echo's every 3 months-All normal
2/09 Staging PET/CT showed 0.2 micronodule upper R lobe-lung-Onc does not think this is mets--
6/5/09 AND 10/09 CT scan 0.2 micronodule unchanged
1/10-PET/CT-uptake in nasopharynx-
1/10-MRI All normal
6/10-Bone Scan-clear
12/10-PET/CT-All Clear-NED
12/11-PET-All Clear-NED

12/12-PET-All Clear-NED
12/13-CT w/contrast Head, Torso-All Clear
12/14-CT w/contrast Head-All Clear
2/15-Core needle biopsy-R scar line

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Old 10-25-2009, 07:53 PM   #4
Rich66
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Location: South East Wisconsin
Posts: 3,431
Re: What is the difference between PET/CT/Bone Scan

I think it may be possible to pick up certain bone mets on a PET but not reliably.
I will also mention that CTs have varying resolutions or "slices", typically between 16 and 64. In cases of tracking mets during chemo, it may be helpful to have a higher slice machine since minute changes may be indistinguishable from differences in where the slices occurred.
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Old 10-25-2009, 07:56 PM   #5
Cal-Gal
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Location: Los Angeles, CA
Posts: 309
Re: What is the difference between PET/CT/Bone Scan

Thanks Rich for this info--
__________________
DX: 11/08 Age: 53
Surgery: 1/09
Bilat Mastectomy, no reconstruction
ILC-4 tumors-1.7 cm,1.5 cm (2).8 cm
DCIS-11 cm
All tumors Grade 3
All tumors ER-0%/PR-0%
All tumors HER2+
IHC-all tumors Overexpression/borderline
FISH 2 tumors Her2-Negative
FISH 2 tumors Her2+ Equivocal
Stage I, 0/1 nodes
LVI-Indeterminate(treated as positive)
SPR Score 8/9
Ki-67 20%
BRCA genetic test 1/2=negative
Chemo: 6 rounds TAC Feb-June 2009 w/Neulasta
Herceptin: 6/12/09-6/4/10 52weeks
HNPCC genetic test: negative
Port Placement-9/23/09 Port Removal 6/25/10
Echo's every 3 months-All normal
2/09 Staging PET/CT showed 0.2 micronodule upper R lobe-lung-Onc does not think this is mets--
6/5/09 AND 10/09 CT scan 0.2 micronodule unchanged
1/10-PET/CT-uptake in nasopharynx-
1/10-MRI All normal
6/10-Bone Scan-clear
12/10-PET/CT-All Clear-NED
12/11-PET-All Clear-NED

12/12-PET-All Clear-NED
12/13-CT w/contrast Head, Torso-All Clear
12/14-CT w/contrast Head-All Clear
2/15-Core needle biopsy-R scar line

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