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Old 10-22-2008, 06:35 PM   #1
Lani
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Join Date: Mar 2006
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Believe 51--not to worry you, just to get you to keep the doctors on their toes!

J Surg Oncol. 2008 Oct 20. [Epub ahead of print]

Multiple primary tumors in men with breast cancer diagnoses-a SEER database review.

Wernberg JA, Yap J, Murekeyisoni C, Mashtare T, Wilding GE, Kulkarni SA.
Department of Surgery, Marshfield Clinic, Marshfield, Wisconsin.
BACKGROUND: Male breast cancer (MBC) comprises 1% of all breast cancers and less than 1% of cancer cases in men. After a diagnosis of MBC, men are at risk of developing a second primary cancer, particularly a second primary breast cancer. The objective of this study is to analyze the characteristics of the population of men diagnosed with a second malignancy, specifically a second MBC. METHODS: Using the Surveillance, Epidemiology, and End Results (SEER) database, 4,873 male patients diagnosed with invasive or in situ breast cancer from 1973 to 2004 were identified and data from patients who developed a second MBC were reviewed. Additional non-breast primary cancer diagnoses were also recorded. RESULTS: A review of 4,966 records corresponding to 4,873 patients revealed 4,462 invasive and 504 in situ breast cancer events. Of the 4,873 patients, 93 (1.9%) were identified with a second MBC. Among the 4,873 patients with MBC, 1,001 (21%) have other non-breast primary cancer diagnoses recorded in the SEER registry. CONCLUSIONS: Although MBC is uncommon, these patients are at risk of a contralateral breast cancer and second primary non-breast cancers. Our findings support that men with breast cancer would benefit from continued long-term surveillance for breast cancer and appropriate screening for non-breast cancers. J. Surg. Oncol. (c) 2008 Wiley-Liss, Inc.
PMID: 18937232
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Old 10-23-2008, 12:13 PM   #2
Believe51
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Join Date: Jun 2007
Location: RHODE ISLAND (Ed getting me a latte on 2nd Cancerversary Cruise 2008) 'BELIEVE': To accept as true or real, To have faith in, To presume ALWAYS BELIEVE
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Thumbs up Hey Santa

No worries. We have been keeping an eye on these things since the start and we so appreciate you, Lani. Right now we do have a reoccurrance going on. Main concerns of course are the Inflammatory aspect of the disease, PSA and prostate and we are exploring the spot on Ed's leg that could be some form of skin cancer.

I love the ammo you send as we do keep others on their toes. He is being studied by so many individuals also. Hopefully any information we gather from his journey will help others.

Wish we had more than a band-aid, we could really use a cure for him and all others.>>Believe51

PS: Getting an entire set of tumor markers for groups of different cancers this week.
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9/7/06Husband 50yrs=StageIV IBC/HER2+,BoneMets10/06TaxotereX10,'H'1X wk,Zometa,Tamoxifen4/12/07Last Tax5/18/07Pet=Rapid Cell Activity,No Organ Mets,Lytic Lesions,Degeneration,Some Bone Repair5/07ChemoFail6/01/07Pleural Thoracentisis=Effusions,NoMalignantCells6/19/07+7/2/07DFCI
6/25/07BrainMRI=BrainMets,Many<9mm7/10/07WBR/PelvisRad37.5Gx15&Nutritionist8/19/07T/X9/20/07BrainMRI=2<2mm10/6/07Pet=BoneProgression
10/24/07ChemoFail11/9/07A/Cx10,EndTam12/7/07Faslodex12/10/07Muga7512/13/07BlasticLesions1/7/08BrainMRI=Clear4/1/08Pet=BoneImprovement,
NoProgression,Stable4/7/08BrainPerfect5/16/08Last A/C8/26/08BrainMets=10(<9mm)9/10/08Gamma10/30/08Met=5mm12/19/08Gamma5mets5
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