Female mice grow new mammary glands from stem cells!!

Cancer an "evolutionary" disease. Here is more evidence that would support that generality.

I have previousy posted that high omega six by reference to omega three (or put another way omega three (DHA) down regulates the expression with reduced omega six) increases the expression of endothelin and CD 40L receptor (tumout necrosis factor receptor family) by a factors of 10 and many others by signicant amounts.

Here is a link for endothelin which is involved in foetal processes.

http://srs.sanger.ac.uk/srsbin/cgi-b...D:131240%5D+-e


Here is a link for CD 40L (there are other links which show a relationship of CD 40L to breast cancer)

http://www.ingentaconnect.com/conten...m8jp.henrietta



I do not have the expertise to put it all together but as a strict amatuer I would guess it is out of the same jigsaw and represents some key bits.

RB


http://www.theage.com.au/news/nation...050495580.html





ABSTRACT

She said the project could serve as a model for understanding the development of other so-called "epithelial" organs (organs that grow from an outer layer of cells) and eventually it might be possible to regrow organs such as the bowel.

An eminent cell biologist at the Walter and Eliza Hall Institute, Doug Hilton, hailed his colleagues' work as "possibly the most significant medical research advance to come out of Melbourne in the past decade".

Importantly, the breakthrough will allow researchers to test an emerging theory on cancer that fundamentally challenges previous ideas on how the disease develops.

Dr Lindeman said yesterday that according to the new theory, mutant, organ-building stem cells — including mammary stem cells — effectively become tumour factories, spawning immortal cancerous cells. Previously, researchers assumed cancerous cells were normal cells immortalised by mutations that had reactivated long-dormant genes involved in embryonic development.