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Old 04-28-2005, 10:42 AM   #1
judiek
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After 15 cycles, 45 treatments, I'm done with my trial. I rec'd my ct results from yesterday...you guessed it...PROGRESSION.
CT CHEST

1.) New small pericardial effusion and new small to moderate size plueral effusion, possibly metastatic.
2.) Slight increase in size of internal mammary and right paracardiac nodes and right hilar nodes since prior study.
3.) Increased right anterior plueral thickening since previous study. Part of this may be related to radiation related change, but cannot exclude plueral metastasis in this area.

CT ABDOMEN/PELVIS

1.) Slightly increasing retroperitoneal and mesenteric adenopathy.
2.) Liver lesions are stable to decreasing in size.

CEA up to 6.0 from .8 last September
CA27.29 is 23 from 22.1

So, fluid and lymph nodes...I know it could have been much worse...the lesions that were in the lungs are still gone at this point. Dr will look at the scans and compare to my CT in January. He will then call me with his suggestions. I'm sad and scared all over again...this tx plan was so manageable and I was comfortable with it.

Thanks for your continued support

warmly,

judiek

History

Discovered lump Sept. 2002 (mammo didn’t pick it up)
Had 3 mammo’s in my 30's...not to sure mammo’s did me any good
Dx Oct 2002-just turned 41
IDC and pagets disease, stage 2B, grade 3/3, nottingham scale 9/9
3cm, lumpectomy,clean margins
er/pr-pos, her2 neg, 2/25 nodes w/cancer
Nov 2002-March 2003-FEC (5fu, epirubicin, cytoxen)
March 2003- started tamoxifen
May 2003- finished rads (33tx)
June 2003-CT/PET Scan- clear
Started 3 month check ups w/lab
Dec 2003-complete hysterectomy
Jan 2004-extensive mets, both lungs & liver(labs normal)
Jan -stopped tamoxifen
Feb CEA-23 (0-3 normal) CA27.29-66.1 (0-38 normal)
Feb 23, 2004 to April 2005 -clinical trial, taxol & avastin
April 15th, -CT-significant shrinkage on all tumors/plueral effusion gone
June 8th -CT-all liver lesions decreased in size/lung mets gone
Aug 9th, -CA27.29 is 22.3, CEA is .8)
Aug 9th, 2004-Brain-CT neg, lung mets/pleural effusion still gone, liver mets had slight shrinkage. Largest hypodesne lesion is 2.1cm, 6 others 1cm or less.
Sept 13th-bone scan negative, mri revealed herniated disc.
Sept 27- Ct of brain, negative/lung mets still gone/ 2 liver lesions gone, 4 under 1cm, 1 @1.7cm.
Nov 29-CT shows stable, lungs still clear, liver tumors stable
Jan 11, 2005-CA27.29 23 / CEA 2.9
Jan 18th, Ct shows disease is still stable
Jan 27th, Brain MRI negative
Feb 8th, -CA27.29 is 22.1 / CEA 3.7
Mar 28th, -CA27.29 is 22.8 / CEA 4.8 (still rising)
April 27th- CA27.29 is 23 /CEA 6.0
April 28th-done with avastin/taxol trial
CT shows new plueral effusion to right lung/enlarged lymph nodes chest and abdomen...liver stable with slight improvement
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Old 04-28-2005, 12:15 PM   #2
brittd01
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Judy,
So sorry to hear about your progression. Something else is going to work for you, I just know it!! Take care and I am thinking of you.
Brittany
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Old 04-28-2005, 04:38 PM   #3
*_anne_*
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I am also sorry to hear this did not work for you. I was hoping that Avastin would be helpful for B.C. There are a lot of different treatments out there and I hope you will find something thath works.
XOXO
Anne
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Old 04-28-2005, 08:36 PM   #4
SusanAnne
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Judie,

I'm sorry your test results were so disappointing. I'm sure you were hoping for some breathing room for a change. Stay strong and see what the next course brings.

All my best,
Susan
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Old 04-28-2005, 09:57 PM   #5
Lolly
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Join Date: Aug 2001
Location: Oregon
Posts: 1,756
Judie, I also am so sorry to hear you're response to this combo wasn't what you hoped for, but you have many options left with other chemos/combos. Hang in there, and keep us posted on what your onc recommends.

<3,
Lolly
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