I was on weekly gemzar from Feb 04 thru May with just a little problem surfacing from time to time, but it finally did me in with exactly the same symptoms you described. I skipped a few weeks and then started with an every other wk chemo schedule. I think that was going to help, but the gemzar quit working and I had to change drugs. Am on xeloda now and don't feel great but not nearly as bad as I did last summer. I had never really felt bad from any chemo drug previously, even with the dreaded adriamycin/cytoxin combo in my initial treatment (prior to recurrence). My onc told me this morning that if I don't feel better (on the xeloda), we will try something else. She already had to cut my dose in half when I initially started the xeloda just before Labor Day because of extreme heartburn, stomach discomfort and weakness. You need to tell your onc how bad you're feeling and explore your options! Your quality of life is very important!! Gemzar stays in your system for a good while, so any change will take a little bit of time to measure its effectiveness. I know exactly how you're feeling and sure hope you can do something to get yourself back on your feet!
Best wishes,
Jackie
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