This explains how estrogens function in post menopausal women in various discrete and regional ways in the body.
It also adds weight as to why fat composition if significant coould rationally be a central factor (omega three / six etc)
http://www.sciencedirect.com/science...178b0c80811d5b
Sources of estrogen and their importance*1
E. R. SimpsonCorresponding Author Contact Information, E-mail The Corresponding Author
Monash Medical Center, Prince Henry’s Institute of Medical Research, P.O. Box 5152, Clayton 3168, Vic., Australia
Available online 4 November 2003.