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03-13-2009, 12:09 PM
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#1
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Webmaster
Join Date: Feb 2005
Location: Home of the "Flying Tomato"
Carlsbad, CA
Posts: 2,036
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Early Detection of Brain Metastases from Advanced Breast Cancer Through Education and
I know several members had tried to enroll in this study, BUT it is still recruiting.
Regards
Joe
Breast cancer is the most common cancer and the second leading cause of cancer death in women. Death is sometimes caused by to the spread of breast cancer to other body systems or metastatic breast cancer (MBC). An increasingly frequent cause of death in patients with MBC is brain metastasis, or cancer in the brain. The Early Detection of Brain Metastases From Advanced Breast Cancer Through Education and Screening is being done to look at the potential value of routine brain imaging in the detection of brain metastases in subjects with advanced breast cancer. It is hoped that information will help doctors in the early detection of brain metastases. The study is also being done to increase awareness about brain metastases in breast cancer patients and the potential benefits of early detection and treatment options available.
Participants in the study must have previously been diagnosed with advanced breast cancer. For the study, advanced breast cancer includes HER-2 positive Stage III or Stage IV breast cancer. Stage III breast cancer is breast cancer that has spread to 4 or more lymph nodes in the armpit, or has spread to the chest wall, skin, or to lymph nodes near the breastbone or collarbone. HER-2 stands for human epidermal growth factor receptor 2. HER-2 helps control how cells grow, divide and repair themselves. Each healthy breast cell contains 2 copies of HER-2, which helps normal cells grow. Sometimes a cell may have too many copies of HER-2. Breast cancer that has too much HER-2 is referred to as HER-2 positive. Stage IV breast cancer is breast cancer that has spread outside of the breast to bones, lungs, brain or other distant lymph nodes or organs in the body, also called metastatic breast cancer, or MBC.
If you meet certain requirements, you may be eligible to participate:
A. Subjects must have an initial primary diagnosis of high-risk and/or HER-2 positive breast cancer. For purposes of this screening study, high-risk breast cancer at initial diagnosis is defined as:
» Stage IV disease, or
» HER-2 positive Stage III disease
B. Subjects must be > = 18 years old.
C. Subjects must be within three to twenty-four months of first metastases or Stage IV diagnosis or within 12 to 24 months of initial diagnosis of HER-2 positive Stage III disease.
D. Subjects must sign a written informed consent form approved by the Institutional Review Board (IRB).
Enrollment is ongoing. For additional information, contact Sandra Davis, Vice President of Endovascular Services and Research, @ 773/250.0423 or sdavis@cinn.org.
__________________
A Proud webmaster to the internet's most informed, educated, COMPASSIONATE and caring group of breast cancer survivors.
Illegitimi non carborundum
My Album
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03-17-2009, 06:02 PM
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#2
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Senior Member
Join Date: Sep 2007
Location: Near Chicago
Posts: 196
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I emailed the address above and then was in contact with the study coordinator. This is a study involving Dr. Rosseau. They need participants. They will accept HER2 Stage III or IV individuals within 36 months of initial diagnosis. I am going to sign up I think. They provide some kind of information or study intro and then a free MRI (with contrast?). I think you can read more about Dr. Rosseau at
http://www.cinn.org/physicians/rosseau-gail.html
Again, they are in need of participants. It sounds easy enough.
Melanie
PS: If you know more about this I'd be glad to hear. Thanks!
__________________
Diagnosed: 7/13/07 (or 7/7/07)
Surgery: 8/15/07 Modified Radical One Side with Lymph Node Dissection
Pathology Report: ER/PR-, HER2+ with FISH at 8.4 copies, Grade 3, Stage IIIa, 3.2 cm tumor plus 4/19 positive lymph nodes
Portacath: 9/7/07
Chemo: 9/14/07 with AC (every three weeks) for four rounds
Physical Therapy for ROM Loss / "Cording" (but not Lymphodema)
Taxol + Herceptin weekly (started 12/2007 with 8 of 12 Taxol)
Radiation: (28 rads from 3/07 to 4/07)
Reconstruction (silicone implant)
Herceptin done (10/08)
Cognitive Remediation (11/08 - 12/08)
Lymphedema Diagnosed 5/10/10 (almost 3 years post cancer diagnosis)
Lymphedema Rehab 9/10/10 - 11/10/10
Six years NED...7/7/2013!
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03-17-2009, 08:46 PM
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#3
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Webmaster
Join Date: Feb 2005
Location: Home of the "Flying Tomato"
Carlsbad, CA
Posts: 2,036
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Melanie,
We coloborated on a joint project several years ago. I am really impressed with their dedication.
I would highly recommend participation in this study. It may lead to improved CNS screening for all stages.
Regards
Joe
__________________
A Proud webmaster to the internet's most informed, educated, COMPASSIONATE and caring group of breast cancer survivors.
Illegitimi non carborundum
My Album
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03-18-2009, 10:03 AM
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#4
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Senior Member
Join Date: Aug 2006
Posts: 492
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Darn, I am more than 36 months from diagnosis. Let me know if they ever change that criteria.
__________________
Are we there yet?
Dx 10/05 IDC, multi-focal, triple +, 5 nodes+
MRM, 4 DD A/C, 12 weekly taxol + herceptin
rads concurrent with taxol/herceptin
finished herceptin 01/08
ooph, Arimidex, bilateral DIEP reconstruction
NED
Univ. of WA, Seattle vaccine trial '07
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