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Old 07-20-2010, 03:44 PM   #1
Chelee
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Location: Southern, CA
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Has this happened to any of you?

I am post-menopausal and I use to have hot flashes. Since I started Femara I haven't had one hot flash? I find this odd. The Femara should be making them worse. I'm certainly not complaining but just wanted to know if anyone else has experience this?
Chelee
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DX: 12-20-05 - Stage IIIA, Her2/Neu, 3+++,Er & Pr weakly positive, 5 of 16 pos nodes.
Rt. MRM on 1-3-06 -- No Rads due to compromised lungs.
Chemo started 2-7-06 -- TCH - - Finished 6-12-06
Finished yr of wkly herceptin 3-19-07
3-15-07 Lt side prophylactic simple mastectomy. -- Ooph 4-05-07
9-21-09 PET/CT "Recurrence" to Rt. axllia, Rt. femur, ilium. Possible Sacrum & liver? Now stage IV.
9-28-09 Loading dose of Herceptin & started Zometa
9-29-09 Power Port Placement
10-24-09 Mass 6.4 x 4.7 cm on Rt. femur head.
11-19-09 RT. Femur surgery - Rod placed
12-7-09 Navelbine added to Herceptin/Zometa.
3-23-10 Ten days of rads to RT femur. Completed.
4-05-10 Quit Navelbine--Herceptin/Zometa alone.
5-4-10 Appt. with Dr. Slamon to see what is next? Waiting on FISH results from femur biopsy.
Results to FISH was unsuccessful--this happens less then 2% of the time.
7-7-10 Recurrence to RT axilla again. Back to UCLA for options.
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Old 07-20-2010, 05:05 PM   #2
Westcoastgirl
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Re: Has this happened to any of you?

I wouldn't say that I have had any hot flashes while on Femara (8 months now), although I must say that I am hot much of the time. My mechanism for heat regulation seems a little off now as I am hot most of the time and then can be cold for a few minutes, then back hot again. This is nothing like the hot flashes I got as I was going through menopause though. I am happy without them to tell you the truth.
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12/17/08 biopsy after two 6 mos mammo recalls
12/30/08 diagnosed high grade IDC & DCIS
ER/PR +, Her2 (+++) post menopausal/age 57
1/15/09 double mastectomy/skin sparing; no evidence of vascular/lymphatic invasion, 8neg/8 nodes (tumor 8.0mm)
2/16/09 given portacath/removed 4/30/10
2/18/09 "surprise" 2.0mm tumor/positive borders~
completed 28 rads 10/09.
2/23/09 until 4/19/10~treatments every 3wks (4 Cytoxan + Adriamycin, 4 Taxol + Herceptin, 13 Herceptin alone)
8/09 osteoporosis diagnosis/Zometa 3 yrs of 1x/6 months
Chemo side effects; Deafness, kidney function loss
11/09 began Aromatase Inhibitor (Femara)/Feb2014, stopped Femara early/after 3 mos began Tamoxifen for 8 mos to complete 5 years
11/10 Reconstruction, directly to silicone implants
12/11 nipples by skin graft/Right breast size reduced

I have heard th
ere are troubles of more than one kind

Some come from ahead and some come from behind.
But I've bought a big bat. I'm all ready you see.
Now my troubles are going to have trouble with me!
Dr. Seuss
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Old 07-20-2010, 07:43 PM   #3
Laurel
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Re: Has this happened to any of you?

Chelee,

My hot flashes were much more intense and frequent on Tamoxifen then on the Femara. Overall I find Femara much easier to tolerate, although the stiffness is a pain (HA! pun intended). I still have a few hot flashes daily, but because they are less intense I am not as aware of them.
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Smile On!
Laurel


Dx'd w/multifocal DCIS/IDS 3/08
7mm invasive component
Partial mast. 5/08
Stage 1b, ER 80%, PR 90%, HER-2 6.9 on FISH
0/5 nodes
4 AC, 4 TH finished 9/08
Herceptin every 3 weeks. Finished 7/09
Tamoxifen 10/08. Switched to Femara 8/09
Bilat SPM w/reconstruction 10/08
Clinical Trial w/Clondronate 12/08
Stopped Clondronate--too hard on my gizzard!
Switched back to Tamoxifen due to tendon pain from Femara

15 Years NED
I think I just might hang around awhile....

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Old 07-21-2010, 03:11 AM   #4
Chelee
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Posts: 2,511
Re: Has this happened to any of you?

Westcoastgirl, What you describe sounds close to what I use to have. I didn't call them a true hot flash as some women deal with. I would get really hot all of a sudden and try to cool down...then I would get the chills and actually put something over me to warm up when it was 80 degrees in here. It was more like my body temperature couldn't regulate. I did notice I use to have a few food triggers too that set them off.

But now since the Femara I have intentionally eaten the foods that use to trigger them and nothing happens. It's actually kind of nice...it's not like I miss having them. I hated breaking out in a sweat in the grocery store or wherever. No worries now. I just find this odd...never heard of this happening before?

Laurel, I agree...stiffness IS a pain. lol It is hard to get going after sitting...but things get better the more I move thank goodness.

Chelee
__________________
DX: 12-20-05 - Stage IIIA, Her2/Neu, 3+++,Er & Pr weakly positive, 5 of 16 pos nodes.
Rt. MRM on 1-3-06 -- No Rads due to compromised lungs.
Chemo started 2-7-06 -- TCH - - Finished 6-12-06
Finished yr of wkly herceptin 3-19-07
3-15-07 Lt side prophylactic simple mastectomy. -- Ooph 4-05-07
9-21-09 PET/CT "Recurrence" to Rt. axllia, Rt. femur, ilium. Possible Sacrum & liver? Now stage IV.
9-28-09 Loading dose of Herceptin & started Zometa
9-29-09 Power Port Placement
10-24-09 Mass 6.4 x 4.7 cm on Rt. femur head.
11-19-09 RT. Femur surgery - Rod placed
12-7-09 Navelbine added to Herceptin/Zometa.
3-23-10 Ten days of rads to RT femur. Completed.
4-05-10 Quit Navelbine--Herceptin/Zometa alone.
5-4-10 Appt. with Dr. Slamon to see what is next? Waiting on FISH results from femur biopsy.
Results to FISH was unsuccessful--this happens less then 2% of the time.
7-7-10 Recurrence to RT axilla again. Back to UCLA for options.
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Old 07-21-2010, 08:19 AM   #5
Jean
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Posts: 3,154
Re: Has this happened to any of you?

Chelee,
Same here!
Have not had a single one...but then I never got them
I was a bit concerned as you if the Femara was doing the job? I had a blood test for estrogen and I was low low .... Also my estrogen level was extremely high 90% and it dropped like a rock.

Hope this info helps you. The Femara is doing its job and you are lucky like me for not having hot flashes.
Not all women have to get them. My Mother who went through menopause naturally never had any either, while both my sisters did.

Best Wishes and hugs being sent to you!
Jean
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Stage 1, Grade 1, 3/30/05
Lumpectomy 4/15/05 - 6MM IDC
Node Neg. (Sentinel node)
ER+ 90% / PR-, Her2+++ by FISH
Ki-67 40%
Arimidex 5/05
Radiation 32 trt, 5/30/05
Oncotype DX test 4/17/06, 31% high risk
TOPO 11 neg. 4/06
Stopped Arimidex 5/06
TCH 5/06, 6 treatments
Herceptin 5/06 - for 1 yr.
9/06 Completed chemo
Started Femara Sept. 2006
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