Back when I was a newbie at this research, I came across a very promising article in the July, 2004 Focus, the Harvard on-line publication, concerning the discovery of the role of Pin1 in the development of Her2+ bc:
http://focus.hms.harvard.edu/2004/Ju.../oncology.html. In fact, the scientists who discovered this created a company called Pintex Pharmaceuticals to develop drugs to target it. The next thing I read was a press release in the Boston Business Journal from April 2005 stating that Pintex had sold all its assets and IP rights to Vernalis PLC, a biotechnology company based in the UK:
http://www.bizjournals.com/boston/st...ml?t=printable. I checked the Vernalis website, but have never seen any drugs to target this pathway under development since. Anyone have any more current information on any research done in this area?
Hopeful