[annmask]

It seems like s/e are different for many of us. I have had 3 doses of Kadcyla, and have headache and fluish symptoms on and of the first week. I feel fatigued the first 2 weeks, well the 3rd. All in all better than chemo as well as Tykerb and trial or targeted therapies I have been on, but harder than I thought it would be. I also have the chemoey taste, and a loss of appetite. I had lost about 8 lbs., but gained it back since I am on steroids for brain mets. Stopping the Kadcyla until June 25 while we treat the brain mets.