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Old 03-31-2012, 11:59 AM   #10
chrisy
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Join Date: Sep 2005
Location: Central Coast, CA
Posts: 3,207
Re: Swollen eyelid, face and neck..in the morning

Sarah,
Well, that is a nasty little detour eh? The hold due to being on heparin is important, as TDM1 does cause significant drop in platelets for most people - they do recover but you don't want to mess around with that plus blood thinning agent. But it sounds like this will not preclude you from getting into the trial, just delay.

Re the brain scan, I am hoping for the best for you on this - remember your noggin was relatively protected by the tykerb/xeloda for a while. So lets expect that there will be nothing of note in your head. Worst case, in some TDM1 studies might not be an exclusion criteria but might delay start. One step at a time tho.

In the meantime, I agree with your approach, try not to think too much! (ha ha)
Good luck on Monday

take care
Chris
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Chris in Scotts Valley
June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?"
9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++
10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response!
04/05 - 4/07 Herception every 3 wks, Continue NED
04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial
06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin
01/08 Progression in liver
02/08 Begin (TDM1) trial
08/08 NED! It's Working! Continue on TDM1
02/09 Continue NED
02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED
12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver
07/11 - 11/11 Herceptin/Xeloda -not working:(
12/11 Begin MM302 Phase I trial - bust:(
03/12 3rd times the charm? AKT trial

5/12 Scan shows reduction! 7/12 More reduction!!!!
8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!)
9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3
11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc
11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go.
2/13 Gemzar/Carbo/Herceptin - no go.
3/13 TACE procedure
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