[Lani]

we still don't even know why people sleep (which seems to be an absolutely fundamental question)

We are still unsure of the causes of Alzheimer's ie, whether the amyloid plaques and neurofibrillary tangles seen under the microscope on autopsies are the cause or an effect. Recent research looking at brains of normals, demented individuals and Alzheimers individuals showed the same brain changes as in Alzheimers in some normal people, and they hypothesized that there are Alzheimers changes and changes that have to do with lack of blood supply and it is the cumulative number of changes and where they are located as well as the "owner of the brain's" makeup in terms of adaptability (plasticity) which may or may not have a genetic bases and/or have environmental contributions which may make the difference.

Since we don't know how the normal brain works, what causes Alzheimers let alone what causes chemobrain, how can we predict if Alzheimers drugs help chemo brain. This article discusses that at least EEG wise, different chemo cocktails cause different brain abnormalities. Since different people metabolize the chemo drugs differently and different people are more or less sensitive to the drugs themselves it will be hard to get enough people with the same/similar genetic makeups, who got the same treatments to determine if Alzheimer drugs helped those treated with AC alone vs those treated with CMF vs those who got AC,T or TCH.

Feel free to scour the literature for case reports or anecdotal evidence for one treatment or the other helping "chemobrain"...but an answer to your question will probably be a long time coming, for the reasons outlined above(and more).