HER2 Support Group Forums - View Single Post - Iodine deficiency ! - falling intakes - goitregens

R.B. · 10-28-2013, 03:57 AM

It occurred to me after writing the above post that I had previously seen a paper linking thyroid dysfunction / goitre with areas know to be low in selenium.

Logically this risk will be greater in areas of high flouride in water and food, the level of other goitrogens in the diet, on the basis that the fluoride may bind with some of the limited available selenium so exacerbating the deficiency.

Selenium is widely recognised as essential to thyroid function, and its absence leads to dysfunction.

http://www.ncbi.nlm.nih.gov/pubmed/12487769

http://www.ncbi.nlm.nih.gov/pubmed/12487769

and

J Pediatr Endocrinol Metab. 2002 Jul-Aug;15(7):1027-31.
Iodine and selenium deficiency in school-children in an endemic goiter area in Turkey.
Aydin K, Kendirci M, Kurtoğlu S, Karaküçük EI, Kiriş A.
Source

Selcuk University Medical Faculty, Konya, Turkey. kursaday@hotmail.com
Abstract

Endemic goiter is one of the most important health problems in Turkey. However, there are not enough studies associated with iodine and selenium status. This study was carried out to establish the effects of iodine and selenium levels on thyroid gland size and thyroid functions in 73 healthy school-children, 7-12 years old (mean 9.56 +/- 1.77 years), 38 girls (52%) and 35 boys (48%), living in an endemic goiter area. Goiter was found in 32 of the children (43.8%) by palpation, and 56 of the children (76.7%) by ultrasonography. Mean serum T3 and TSH levels were in the upper limit of normal, and mean serum T4 levels were within the normal limits, but mean serum thyroglobulin levels were higher than the normal limits. Mean serum selenium level was 30.84 +/- 23.04 microg/l, and mean urinary iodine level was 3.91 +/- 3.77 microg/dl, appropriate for moderate iodine and selenium deficiency. Thyroid volumes of the children were negatively correlated with serum selenium levels, but there was no correlation with urinary iodine levels and thyroid hormones. In conclusion, school-children in this area had significant goiter problems, probably due to the iodine and selenium deficiencies.

10-28-2013, 03:57 AM	#49
R.B. Senior Member Join Date: Mar 2006 Posts: 1,843	Re: Iodine deficiency ! - falling intakes - goitregens - competition bromine and fluo It occurred to me after writing the above post that I had previously seen a paper linking thyroid dysfunction / goitre with areas know to be low in selenium. Logically this risk will be greater in areas of high flouride in water and food, the level of other goitrogens in the diet, on the basis that the fluoride may bind with some of the limited available selenium so exacerbating the deficiency. Selenium is widely recognised as essential to thyroid function, and its absence leads to dysfunction. http://www.ncbi.nlm.nih.gov/pubmed/12487769 http://www.ncbi.nlm.nih.gov/pubmed/12487769 and J Pediatr Endocrinol Metab. 2002 Jul-Aug;15(7):1027-31. Iodine and selenium deficiency in school-children in an endemic goiter area in Turkey. Aydin K, Kendirci M, Kurtoğlu S, Karaküçük EI, Kiriş A. Source Selcuk University Medical Faculty, Konya, Turkey. kursaday@hotmail.com Abstract Endemic goiter is one of the most important health problems in Turkey. However, there are not enough studies associated with iodine and selenium status. This study was carried out to establish the effects of iodine and selenium levels on thyroid gland size and thyroid functions in 73 healthy school-children, 7-12 years old (mean 9.56 +/- 1.77 years), 38 girls (52%) and 35 boys (48%), living in an endemic goiter area. Goiter was found in 32 of the children (43.8%) by palpation, and 56 of the children (76.7%) by ultrasonography. Mean serum T3 and TSH levels were in the upper limit of normal, and mean serum T4 levels were within the normal limits, but mean serum thyroglobulin levels were higher than the normal limits. Mean serum selenium level was 30.84 +/- 23.04 microg/l, and mean urinary iodine level was 3.91 +/- 3.77 microg/dl, appropriate for moderate iodine and selenium deficiency. Thyroid volumes of the children were negatively correlated with serum selenium levels, but there was no correlation with urinary iodine levels and thyroid hormones. In conclusion, school-children in this area had significant goiter problems, probably due to the iodine and selenium deficiencies. Last edited by R.B.; 10-30-2013 at 06:54 AM..