HER2 Support Group Forums - View Single Post - What can we do about the delay of TDM-1

Trish · 09-21-2010, 07:18 PM

Thank you for all the work you are doing to get the TDM-1 decision reversed. My liver mets progressed on both Herceptin and Tykerb after initial positive responses (despite liver mets growing and sky high tumour markers I feel ridiculously healthy) so was really disappointed about the recent FDA decision. I live in Australia and Genentech won't apply to our Pharmaceutical Benefits Scheme until they get FDA approval. Hence my gratitude for the work you are doing. I am so frustrated by the one size fits all mentality. I hope Personalised Medicine is gaining ground (I see there is a big conference at Harvard Medical School on November) and just hope it can have some influence on bodies such as FDA and PBS here in Aust.
I will keep racking my brains about anything I can do from here.
I find it so sad to see the excited post from Joe about the expanded access for TDM-1. He tried so hard for us and I am ever grateful.
Trish
Trish

09-21-2010, 07:18 PM	#57
Trish Senior Member Join Date: May 2010 Location: Melbourne, Australia Posts: 434	Re: What can we do about the delay of TDM-1 Thank you for all the work you are doing to get the TDM-1 decision reversed. My liver mets progressed on both Herceptin and Tykerb after initial positive responses (despite liver mets growing and sky high tumour markers I feel ridiculously healthy) so was really disappointed about the recent FDA decision. I live in Australia and Genentech won't apply to our Pharmaceutical Benefits Scheme until they get FDA approval. Hence my gratitude for the work you are doing. I am so frustrated by the one size fits all mentality. I hope Personalised Medicine is gaining ground (I see there is a big conference at Harvard Medical School on November) and just hope it can have some influence on bodies such as FDA and PBS here in Aust. I will keep racking my brains about anything I can do from here. I find it so sad to see the excited post from Joe about the expanded access for TDM-1. He tried so hard for us and I am ever grateful. Trish Trish __________________ 5/2004 (R) 30mm bre gr3 infiltrating ductal ca 16/18nodes er (2+) pr (3+) HER2 (3+) 6/2004 6 cycles(FEC), Oct 40 rads, Tamoxifen 5/2006 oopherectomy, Arimedex 12/2006 liver mets largest 9cm 1/2007 Herceptin, 3/2007 Taxol + Herc 1/2008 Herc alone 4/2008 Multiple bone mets,Zometa 7/2008 Herc + Gemcitabine 8/2008 Herc+Navelbine/vinoralbine 10/2008 Herc+Carboplatin+Taxol 12/2008 Tykerb+Xeloda 2/2010 Herceptin + trial drug 5/2010 Herceptin+Tykerb 8/2010 Tykerb+Abraxane 9/2010 Abraxane 12/2010 Abraxane+Tyk+Herc 4/2011 Tyk+Herc+Femara 6/2011 Liver and bone mets prog.Abraxane continue Herceptin,Tykerb,Femara and Zometa 8/2011 Probable liver progression and increased neuropathy. Xeloda with Tyk+Herc. Zometa 6 weekly. 9/2011 Liver progression,TM +++. Cyclophosphamide and Methotrexate metro Herc Zometa 10/2011 liver mets prog.Herc, 3 Tykerb +2mg decodron daily,Zometa