HER2 Support Group Forums - View Single Post - Why do I read posts saying hercept not working

linn65 · 07-20-2013, 11:01 AM

Lani,

If I am understanding you correctly than the reason for my ER+ 30 per my core biopsy vs ER+ 73 masectomy biopsy would mean the herceptin is doing its job in killing the HER2+++ (does That mean amplified). However, that pesky ER weed starting growing due to lack of competion, right? Now, the tamoxifen is the treatment for ER+ and that is why women later choose to remove their ovaries???

It seems basically doing neo adjunctive therapy gives a baseline of how your cancer will respond. Then, after surgery the more precise biopsy, can help a person learn what might work best?

What is serial imaging? And when you speak of pathways what does that mean? Does it mean cancer isn't growing this way due to treatment so it tries to find another pathway to grow?

Who needs packing just throw some clothes in that suit case this is much more interesting.��

07-20-2013, 11:01 AM	#14
linn65 Senior Member Join Date: Dec 2012 Location: Attica, IN Posts: 371	Re: Why do I read posts saying hercept not working Lani, If I am understanding you correctly than the reason for my ER+ 30 per my core biopsy vs ER+ 73 masectomy biopsy would mean the herceptin is doing its job in killing the HER2+++ (does That mean amplified). However, that pesky ER weed starting growing due to lack of competion, right? Now, the tamoxifen is the treatment for ER+ and that is why women later choose to remove their ovaries??? It seems basically doing neo adjunctive therapy gives a baseline of how your cancer will respond. Then, after surgery the more precise biopsy, can help a person learn what might work best? What is serial imaging? And when you speak of pathways what does that mean? Does it mean cancer isn't growing this way due to treatment so it tries to find another pathway to grow? Who needs packing just throw some clothes in that suit case this is much more interesting.�� __________________ myleftlump.wordpress.com - started blogging my IDC breast cancer 7/2012 diagnosed with multiple solid lesions 7/20/12 biopsy done. ER+ 30 PR -, HER+++,k167 80% Grade 2 9/2012 biopsy on lymph node - showed malignant 9/2012 Pre-adjunctive TCH chemo. 12/6/12 MRI after Pre-adj. Results: Modest Decrease in size of left breast malignancy As well as the associated satellite lesions and auxiliary Adenopathy compared to prior study. Doctors hoped for better but good response it didn't grow. 12/18/2012 left masectomy with axillary nodes Size 3.2 CM, Nottingham score 9/9 Grade 3, no evidence of in situ carcinoma Areas of angiolymphatic are identified Carcinoma is 0.5 cm from inked deep Margin of excision Attached axillary lymph nodes: metastatic Carcinoma in 6 of 8 nodes. Size of largest node 1.5 cm Extracapsular ER + 73%, PR+2%, HER2+ 2/27/13 6 weeks of IMRT radiation finished 2/2013 Started on Tamoxifan 5 years. 8/2013 will take last Herceptin, 17 treatments total every 3 weeks. BRCA1 & BRAC2 - Negative August 28, 2013 DIEP flap on the left breast. February 2014 Nip & Tuck March 14, 2014 nipple reconstruction and removed port. August 14, 2014 lump in lymph nodes under arm and above clavicle. Stage IV August 28, 2014 herceptin And projeta starting and port put back in. 3/18/15 stopped arimidex. 3/18/15 progression....Tdm1