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chrisy · 04-17-2007, 09:28 AM

Hi friends,

HEY, My liver's back!

I got the results of last week's PET/CT scan, which was done to clarify and get more information on the new recurrence in my liver.

The good news (I guess!) is that the left lobe of my liver, which the original scan reported appeared absent, is back! The not so good news is, there is a 3.5x2.3cm lesion there, in addition to the 1.5cm one in the right lobe. That actually makes sense, as with my previous recurrence the left lobe was pretty much "completely involved"

So, although I enjoyed my little boat trip on "de-nile" , I guess it's time to add some bigger, or at least different, guns. I've got a couple of more hoops to jump through first, but I expect to start on a clinical trial of Tykerb + Avastin next week. I will be under the care of Dr. Hope Rugo, so I know I am in good hands. In her words yesterday, I lose nothing by trying this combination which could work for some time...and then I STILL have all the chemo options. Yippee!

So, although I'm a little discouraged (My heart really sank when I got that news), I'm not ready to quit yet!

Thanks for all your support.

04-17-2007, 09:28 AM	#1
chrisy Senior Member Join Date: Sep 2005 Location: Central Coast, CA Posts: 3,207	Not the news I was hoping for... Hi friends, HEY, My liver's back! I got the results of last week's PET/CT scan, which was done to clarify and get more information on the new recurrence in my liver. The good news (I guess!) is that the left lobe of my liver, which the original scan reported appeared absent, is back! The not so good news is, there is a 3.5x2.3cm lesion there, in addition to the 1.5cm one in the right lobe. That actually makes sense, as with my previous recurrence the left lobe was pretty much "completely involved" So, although I enjoyed my little boat trip on "de-nile" , I guess it's time to add some bigger, or at least different, guns. I've got a couple of more hoops to jump through first, but I expect to start on a clinical trial of Tykerb + Avastin next week. I will be under the care of Dr. Hope Rugo, so I know I am in good hands. In her words yesterday, I lose nothing by trying this combination which could work for some time...and then I STILL have all the chemo options. Yippee! So, although I'm a little discouraged (My heart really sank when I got that news), I'm not ready to quit yet! Thanks for all your support. __________________ Chris in Scotts Valley June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?" 9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++ 10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response! 04/05 - 4/07 Herception every 3 wks, Continue NED 04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial 06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin 01/08 Progression in liver 02/08 Begin (TDM1) trial 08/08 NED! It's Working! Continue on TDM1 02/09 Continue NED 02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED 12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver 07/11 - 11/11 Herceptin/Xeloda -not working:( 12/11 Begin MM302 Phase I trial - bust:( 03/12 3rd times the charm? AKT trial 5/12 Scan shows reduction! 7/12 More reduction!!!! 8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!) 9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3 11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc 11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go. 2/13 Gemzar/Carbo/Herceptin - no go. 3/13 TACE procedure