HER2 Support Group Forums - View Single Post - breast cancer stem cells--are luminal B from ER- stem cells?

Becky · 10-24-2006, 05:44 AM

Does anyone know the real difference between Luminal A and B? I always thought A is highly ER and PR positive whereas Luminal B is less than 50% positive for either receptor with perhaps one or the other receptor negative. Therefore, Luminal B with a positive Her2 acts more like Her2 + ER/PR neg.

Any thoughts here?

kind regards

Becky

10-24-2006, 05:44 AM	#3
Becky Senior Member Join Date: Sep 2005 Location: Stockton, NJ Posts: 4,179	Does anyone know the real difference between Luminal A and B? I always thought A is highly ER and PR positive whereas Luminal B is less than 50% positive for either receptor with perhaps one or the other receptor negative. Therefore, Luminal B with a positive Her2 acts more like Her2 + ER/PR neg. Any thoughts here? kind regards Becky