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Re: TDM-1 side effects
Barb had her second treatment Tuesday after an uneventful first on the 28th of Aug. She did feel some pain in the tumor site in her left breast but felt like it was more in her shoulder. Now after the second treatment she has developed a cough and felt achy all over Wednesday. Its so hard to know what is treatment related and what may simply be a bug. We had our two grandsons over Tuesday night only to find out yesterday that the oldest had to leave school yesterday and threw up when he got home. Just what Barb needs right? She said she felt OK this morning but didnt get a good nights rest. Personally I think theres a war going on at the tumor site in her breast and those little TDM-1 boogers are kicking some cancer A_ _.
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Diag. Aug. 2010
ER- PR- Her-2 +++ Stage IV
Mets to T 6th Vertabrae
Radiation to spine
10/23/10StartNavelbine
11/19/10 Port installed
11/22/10 Started 2nd cycle
1/10/11 Finished 2nd cycle
1/24/11 Herceptin Only
3/7/11 progression, start Taxol/Herceptin
4/18/11 Skin mets appear increase treatments to weekly
rash spreads to right breast
7/5/11 enroll in TDM-1 study
7/29/11 randomly assigned Tykerb drop out of trial and start Tykerb /Herceptin no Xeloda skin mets gone Tykerb working
1/31/12 Skin mets return add Xeloda
5/9/12 Stop Tykerb skin mets back
5/17/12 Return to Navelbine/Herceptin
6/26/12 start process for TDM-1 compassionate access
8/28/12 Start TDM-1
10/9/12 third TDM-1 no response yet
10/23/12 Start Haloven
1/17/12 Start Perjeta/ Herceptin/Taxotere
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