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Old 10-08-2008, 12:25 PM   #3
Lani
Senior Member
 
Join Date: Mar 2006
Posts: 4,778
at least two companies seem to be in trials with a mAb vs TRAIL receptor 2

one is AMGEN who make denosumab, mAb vs RANKL, who have 5 active trials


A Phase 1b/2 Study of AMG 655 in Combination With Paclitaxel and Carboplatin for the First-Line Treatment of Advanced Non-Small Cell Lung Cancer




Phase II, Phase I




20060295
NCT00534027







2.
Phase 1b/2 Study of AMG 655 With mFOLFOX6 and Bevacizumab for First-Line Metastatic Colorectal Cancer




Phase II, Phase I




Active


18 and over



20060464
NCT00625651







3.
Phase 1b/2 Study of AMG 655 With Doxorubicin for the First-Line Treatment of Unresectable Soft Tissue Sarcoma





Phase II, Phase I



Pharmaceutical / Industry


20060324
NCT00626704







4.
A Study of AMG 655 or AMG 479 in Combination With Gemcitabine for Treatment of Metastatic Pancreatic Cancer





Phase II, Phase I







20060323
NCT00630552







5.
AMG 655/Panitumumab Combination Metastatic Colorectal Cancer Study
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