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Old 11-14-2013, 04:58 PM   #72
R.B.
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Join Date: Mar 2006
Posts: 1,843
Re: Iodine deficiency ! - falling intakes - goitregens - competition bromine and fluo

This is the paper I mention above.

It is fascinating because it suggests that calcium in the diet through milk can mitigate the effect of fluorine intake, it is presumed by reducing the uptake of fluorine by the gut.

Further those that drank from well where the water was higher in calcium also appear protected, even though they had relatively high intakes of fluorine. Those that had higher fluoride plus low calcium saw a high incidence of dental fluorosis.

There is no information on selenium zinc magnesium iron etc.

Seaweed is apparently in relative terms very high in calcium; might calcium in seaweed explain why there is no widespread suggestion that fluorosis was an problem in Hokkaido. Would this also explain why fish such as sardines are not associated with fluorosis or thyroid issues, because the bones which are high in fluoride are also high in calcium.

Apparently other studies has suggested vitamin D may also be a factor in fluorosis.

The paper states it was unable to show a direct association between fluoride intake and the occurrence of fluorosis.

Poor absorption of fluoride may explain why its effects are limited in other high fluoride areas.

All of which suggests it is important in fluoride studies to look at urinary fluoride, (so uptake as well as intake is known) and it would also be informative if iodine in the diet and in urine was measured too (to help tease out the roots of hyperthyroidism).

So as usual in human biology it appears that mechanisms are multifaceted and widely interconnected.





Groundwater quality and its health impact: An assessment of dental fluorosis in rural inhabitants of the Main Ethiopian Rift
Tewodros Rango a,⁎, Julia Kravchenko b, Behailu Atlaw c, Peter G. McCornick d, Marc Jeuland e, Brittany Merola a, Avner Vengosh a

PDF full version

http://www.google.com/url?sa=t&rct=j...TKiKToDzS3Lm2Q




PS. I have spent quite a while searching for papers on the displacement in the body of iodine by fluorine in T3 and T4 without much success so far. It does appear at least the first step can be created in the lab.

Last edited by R.B.; 11-14-2013 at 05:21 PM..
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