HER2 Support Group Forums - View Single Post - Intrathecal (IT) Herceptin (Trastuzumab) for brain mets (Leptomeningeal Metastases)

marvass · 05-05-2012, 01:23 PM

Got to know that in small dose, less than 50 mg it does not work.
At chicago trial the dose is low while in off protocol they are giving 100 mg or so and it is curing most of those trying it.
There are three papers talking about IT herceptin and they both conclude that it was successful. Simply cannot understand why not much are doing it.

05-05-2012, 01:23 PM	#5
marvass Senior Member Join Date: May 2012 Posts: 105	Re: Intrathecal (IT) Herceptin (Trastuzumab) for brain mets (Leptomeningeal Metastase Got to know that in small dose, less than 50 mg it does not work. At chicago trial the dose is low while in off protocol they are giving 100 mg or so and it is curing most of those trying it. There are three papers talking about IT herceptin and they both conclude that it was successful. Simply cannot understand why not much are doing it.