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fullofbeans · 08-28-2011, 12:21 PM

Thanks all

Sheila, sorry to hear that you progressed on tdm1 and by the look o it tyk/herc did not help for long at all..how are you doing on gemzar (it's gemcetabine right?) and what side effcet had you had? I am thinking low dose gem..I am thinking that perhaps people that do not respond to tyk/herc may not respond to tdm1..

Hutch, no worries about your post, it may help someone else tho

Julie, you did not fail tyk/herc they failed you! Had you responded o Tyk/herc? did it keep it in check or stable for any amount of time?

Ellie, also bc groups are focused on research as you say because they do not feel in immediate danger, unlike stage 3 & 4. hiv patient are/were all under the same amocles sword and knew that their turn would come, not simply in 20% of the case..and they do not know what we have to go through to get treatments and how humiliating it is to be ramdomised (and not be offered the drug if you prog) and excluded for this and this.

08-28-2011, 12:21 PM	#12
fullofbeans Senior Member Join Date: Jan 2007 Location: UK Posts: 617	Re: Does tdm1 work after herc+Tyk Thanks all Sheila, sorry to hear that you progressed on tdm1 and by the look o it tyk/herc did not help for long at all..how are you doing on gemzar (it's gemcetabine right?) and what side effcet had you had? I am thinking low dose gem..I am thinking that perhaps people that do not respond to tyk/herc may not respond to tdm1.. Hutch, no worries about your post, it may help someone else tho Julie, you did not fail tyk/herc they failed you! Had you responded o Tyk/herc? did it keep it in check or stable for any amount of time? Ellie, also bc groups are focused on research as you say because they do not feel in immediate danger, unlike stage 3 & 4. hiv patient are/were all under the same amocles sword and knew that their turn would come, not simply in 20% of the case..and they do not know what we have to go through to get treatments and how humiliating it is to be ramdomised (and not be offered the drug if you prog) and excluded for this and this. __________________ 35 y/o June 06: BC stage I Grade 3; ER/PR neg Her-2+++; lumpectomies Aug 06: Stage IV liver mets: 6 tumours July 06 to Jan 07: 2FEC+6Taxotere; 3TACE; LITT March 07- Sept 07: Vaccination trial (phase 2, peptide based) at the UW (Seattle). Herceptin since 2006 NED til Oct 09 Recurrence Oct 2009: to internal mammary gland since October 2009 missed on Oct and March 2010 scan.. palpable nodes in May 2010 when I realised.. Nov 2011:7 mets to lungs progressing fast failed hercp/tykerb/xeloda combo.. superior vena cava blocked: stent but face remains puffy April 2012: Teresa Trial, randomised to TDM1 Nov 2012 progressing on TDM1 Dec 2012 blockage of my airways by tumours, obliteration of these blocking tumours breathing better but hoping for more- at mo too many tumours to count in the lungs and nodes. Dec 2012 Starting new trial S-222611 phase 1b dual egfr her2+ inhibitor. 'Under no circumstances should you lose hope..' Dalai Lama Last edited by fullofbeans; 08-28-2011 at 06:09 PM..*