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Re: Study explains control of cell metabolism in breast cancer
The article is stating that the proteins that carry the glutamate are broken down so the tumor has an insufficient supply of glutamate. The article is on the research on Taxanes only, not other drugs.
It says specifically taxanes, so therefore, until someone does the research on other drugs that question can't be answered. Since the main mechanism of Taxane drugs is to inhibit the process of cell division and it is one of the most popular chemo drugs, that is most likely why they started with the taxanes.
Again, everybody has different levels of amino acids and proteins and sometimes you cannot see any manifestation of those interactions among the cells. Basically you may have certain levels but you see no pre condition.
There are no real answers to your questions. I would gather it would demand further research.
jean
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Stage 1, Grade 1, 3/30/05
Lumpectomy 4/15/05 - 6MM IDC
Node Neg. (Sentinel node)
ER+ 90% / PR-, Her2+++ by FISH
Ki-67 40%
Arimidex 5/05
Radiation 32 trt, 5/30/05
Oncotype DX test 4/17/06, 31% high risk
TOPO 11 neg. 4/06
Stopped Arimidex 5/06
TCH 5/06, 6 treatments
Herceptin 5/06 - for 1 yr.
9/06 Completed chemo
Started Femara Sept. 2006
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