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Old 06-25-2007, 06:13 AM   #1
RobinP
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Join Date: Nov 2005
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Breastfeeding increased risk her2+ bc...

Breastfeeding was associated with a 4-fold increased risk only for breast cancer that overexpressed HER-2/neu in this particular article:

http://cebp.aacrjournals.org/cgi/content/full/9/1/65

Also, prolactin protects bc cells against apoptosis or cell death:
http://www.nature.com/bjc/journal/v91/n2/abs/6601947a.htm

Also, oxytocin has a antiproliferative effect on bc cells through the PKA pathway, which inhibits Ras and proliferation:
http://www.ncbi.nlm.nih.gov/sites/en...&dopt=Abstract

PS I breastfeed about a year before I got bc. Interesting.
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Robin
2002- dx her2 positive DCIS/bc TX Mast, herceptin chemo
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