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Old 01-01-2016, 02:42 PM   #112
R.B.
Senior Member
 
Join Date: Mar 2006
Posts: 1,843
Re: Iodine deficiency ! - falling intakes - goitregens - competition bromine and fluo

How time flies!

Just found this looking for something else.

This is an excellent paper on iodine selenium and breast cancer, which emphasizes the interconnected nature of selenium and iodine and need for adequate amounts of both.

It also considers the relevance of fibrocystic breast disease, and the relevance of iodine thereto.

It also links in thyroid function.

It also recognizes that iodine is transported by other mechanisms than thyroxine including attachment to fats.

It was written in 2000 and emphasizes the need for more research which is still required in 2016.

It is available in full for free as a PDF.


Hypothesis: Iodine, selenium and the development of breast cancer

http://www.iodineresearch.com/files/...ast_cancer.pdf

An abstract

"High-grade fibrocystic disease (i.e., ductal or lobular
hyperplasia, but especially atypical hyperplasia) is gen-
erally believed to be a precursor to ductal carcinoma
in situ (DCIS) and subsequent invasive/metastatic car-
cinoma. Other symptoms of benign breast disease,
including cyclical mastalgia [12] and apocrine cysts
[13], have also been associated with an increased breast
cancer risk. In the USA it has been estimated that 50±
90% of women experience Fibrocystic disease during
their lifetime [14, 15]; a rate so high that some have
suggested that this condition should no longer be
classiÆed as a disease [14, 15]. However, downgrading
the disease status simply due to prevalence estimations is
questionable when this condition, in populations at low
risk for breast cancer, is so much less common [16].
Gravelle et al. [17] found that healthy British women
had signiÆcantly less low-risk (low-density) and a
greater proportion of high-risk (high-density) breast
parenchymal patterns than Japanese women. Further-
more, immigration studies suggest that these breast
parenchymal patterns may be inØuenced by nongenetic
factors. For example, Sasamo et al . [18] found that the
prevalence of breast epithelial hyperplasia was similar
between Japanese women (18.4%) and Japanese issei
Hawaiians (immigrant generation) (14.5%), but signif-
icantly lower than nisei Hawaiians (second generation)
(51.4%)."
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