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I am on herceptin every three weeks, almost one year now and finished chemo a year ago. I have noticed that my fatigue has gotten worse while being on herceptin. And it seems like the longer I do it the worse it gets. Memory problems have also gotten a lot worse. I've had splitting fingernails and small weight gain that is almost impossible to get rid of. I developed a rash that has since gone away with treatment of it.
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