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hi jacci, I am on that regimen and trying to stay positive. I am on my third cycle and this regimine has kicked my butt- diarrhea, hands and foot syndrome, rash and now I have to take a pill cause every time I eat I get horrible cramps. My onc has the reduced the dose of both drugs to two and two on the xeloda and now down to 2 tykerb a day. My onc said I am probably missing a enzime which would matabalize the drug. I must stress that every persons body reacts differently to each drug.I am praying you will no side effects.Good luck, linda
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