HER2 Support Group Forums - View Single Post

donocco · 02-05-2019, 03:28 PM

Jules

I took a quick glance at DS8201. It is Herceptin combined with Deruxtecan and seems to have a good effect in the phase i studies. I tried to find out what Deruxtecan is and didnt have much luck but it probably is frelated to Topotecan (Hycamptin) which is a topoisomerase inhibitor like Etoposide. May be worth looking into

Paul

PS I had no idea Adriamycin was a topoisomerase inhibitor until Becky put that post on the board.

02-05-2019, 03:28 PM	#100
donocco Senior Member Join Date: Oct 2013 Posts: 474	Re: Treatment after Kadcyla? Jules I took a quick glance at DS8201. It is Herceptin combined with Deruxtecan and seems to have a good effect in the phase i studies. I tried to find out what Deruxtecan is and didnt have much luck but it probably is frelated to Topotecan (Hycamptin) which is a topoisomerase inhibitor like Etoposide. May be worth looking into Paul PS I had no idea Adriamycin was a topoisomerase inhibitor until Becky put that post on the board.