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Old 02-23-2012, 09:08 PM   #12
chrisy
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Join Date: Sep 2005
Location: Central Coast, CA
Posts: 3,207
Re: My 2 year run is over

Dear emelie,
Although a biopsy is not fun, in the long run it is important to know what you are dealing with. Tumor biology can change, and is the key to finding the best treatment options.

I've had 3 biopsies of my liver, once when first dx with meta (in part because they couldn't believe it was from the "cured" DCIS. Then one last summer to be sure we still knew the her2 and ER/PR status. And one in December which was required as part of a clinical trial.

It is an outpatient procedure. The first two went without hitches, uncomfortable but doable, and I was up and about feeling pretty much back to normal in a day or so. I had some complications with the last one (some bleeding - a perfect storm of low platelets, vascular tumor and large bore needle!) which won me a night in a luxury room with views of SF bay and bridge while being "observed" as a precaution, but was still up and recovered similarly to the other two. Not trying to scare you off, its a small risk, the radiologist hadnt ever had that happen and he was royally p.o.'d, That was the "small risk" thing, guess it was just my turn!

Anyway, I do think it's worth it to get whatever info you can, the better to choose weapons my dear!

Hang in there.
Chris
__________________
Chris in Scotts Valley
June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?"
9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++
10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response!
04/05 - 4/07 Herception every 3 wks, Continue NED
04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial
06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin
01/08 Progression in liver
02/08 Begin (TDM1) trial
08/08 NED! It's Working! Continue on TDM1
02/09 Continue NED
02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED
12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver
07/11 - 11/11 Herceptin/Xeloda -not working:(
12/11 Begin MM302 Phase I trial - bust:(
03/12 3rd times the charm? AKT trial

5/12 Scan shows reduction! 7/12 More reduction!!!!
8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!)
9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3
11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc
11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go.
2/13 Gemzar/Carbo/Herceptin - no go.
3/13 TACE procedure
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