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That is weird because everything you will read about tykerb will tell you that it does cross the brain barrier - that's what is so great about tykerb to hopefully protect the brain from tumors. I have not heard of having headaches with tykerb/xeloda. The biggest side effects I know of are diarhea, nauseau, some vomiting,fatigue, rash on hands and feet - if you look up the drugs you will beable to see the side effects for yourself. You should let your Dr. know about the headaches because you should beable to get something for that. Also, sometimes it takes a few days till your body adjusts - do you have other side effects?
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