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StephN · 10-21-2008, 02:32 PM

"Living Proof II" - GREAT idea. There would be plenty of information once those first trials were over and the data was accepted by FDA. We have TEN YEARS' worth, for Heaven's sake!!!

There was the problem of "humanizing" the mouse antibody so that our bodies would not fight it off before it could get to the tumors. Plus the problem of how to make MORE of it so that it could reach the waiting masses of patients. Here is where the Chinese Hamsters come in. (Are you listening, TipToe?)

Then we have the next set of trials with Taxol and then the HERA and adjuvent therapy trials here. So we did not just go from those trials in the movie to Herceptin being available to everyone.

Not mention the many stage IV patients who have their lives to live due to getting long term Herceptin (with or without other drugs).

The early story sprang from a sort of Hollywood "fairy tale" and Renee Zellweger may not have interest in the follow on. However, I would bet my next summer's roses that Dr. Slamon would happily cooperate.

10-21-2008, 02:32 PM	#10
StephN Senior Member Join Date: Nov 2004 Location: Misty woods of WA State Posts: 4,128	"Living Proof II" - GREAT idea. There would be plenty of information once those first trials were over and the data was accepted by FDA. We have TEN YEARS' worth, for Heaven's sake!!! There was the problem of "humanizing" the mouse antibody so that our bodies would not fight it off before it could get to the tumors. Plus the problem of how to make MORE of it so that it could reach the waiting masses of patients. Here is where the Chinese Hamsters come in. (Are you listening, TipToe?) Then we have the next set of trials with Taxol and then the HERA and adjuvent therapy trials here. So we did not just go from those trials in the movie to Herceptin being available to everyone. Not mention the many stage IV patients who have their lives to live due to getting long term Herceptin (with or without other drugs). The early story sprang from a sort of Hollywood "fairy tale" and Renee Zellweger may not have interest in the follow on. However, I would bet my next summer's roses that Dr. Slamon would happily cooperate. __________________ "When I hear music, I fear no danger. I am invulnerable. I see no foe. I am related to the earliest times, and to the latest." H.D. Thoreau Live in the moment. MY STORY SO FAR ~~~~ Found suspicious lump 9/2000 Lumpectomy, then node dissection and port placement Stage IIB, 8 pos nodes of 18, Grade 3, ER & PR - Adriamycin 12 weekly, taxotere 4 rounds 36 rads - very little burning 3 mos after rads liver full of tumors, Stage IV Jan 2002, one spot on sternum Weekly Taxol, Navelbine, Herceptin for 27 rounds to NED! 2003 & 2004 no active disease - 3 weekly Herceptin + Zometa Jan 2005 two mets to brain - Gamma Knife on Jan 18 All clear until treated cerebellum spot showing activity on Jan 2006 brain MRI & brain PET Brain surgery on Feb 9, 2006 - no cancer, 100% radiation necrosis - tumor was still dying Continue as NED while on Herceptin & quarterly Zometa Fall-2006 - off Zometa - watching one small brain spot (scar?) 2007 - spot/scar in brain stable - finished anticoagulation therapy for clot along my port-a-catheter - 3 angioplasties to unblock vena cava 2008 - Brain and body still NED! Port removed and scans in Dec. Dec 2008 - stop Herceptin - Vaccine Trial at U of W begun in Oct. of 2011 STILL NED everywhere in Feb 2014 - on wing & prayer 7/14 - Started twice yearly Zometa for my bones Jan. 2015 checkup still shows NED 2015 Neuropathy in feet - otherwise all OK - still NED. Same news for 2016 and all of 2017. Nov of 2017 - had small skin cancer removed from my face. Will have Zometa end of Jan. 2018.