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Neupogen gave me very bad bone pain, so bad that I woke up one night unable to move, but I found that plain panado, if taken regularly as pain management worked. don't skip doses though, and don't let the pain get to an unmanagable level. The issue I am struggling with is that it is two weeks after last dose of neupogen and I am still getting joing and bone pain. Not as bad as during the injections, but enough to make me concerned. Has anyone on neupogen experienced that?