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Old 03-19-2010, 09:46 AM   #19
Barbara2
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Join Date: Sep 2005
Location: South Dakota.
Posts: 621
Re: Risk of Recurrent Disease in HER2-Positive Patients

I agree with Jean's thoughts here:
Do you remember 2yrs. ago when I talked to you about a tune up approach with herceptin. I really believe that after 5 yrs. on AI and surgery behind us, etc. we may need a booster of Herceptin. Are there any trials of herceptin going on like this? I only know of one trial of herceptin for DCIS at this time.

In 2003 I posted a question (this board had a different name at that time) asking if anyone knew of a treatment or anything available to breast cancer patients that could be taken after adjuvent therapy, in an effort to keep the cancer from recurring. I received a reply from someone who said she did not know of anything of that sort and hadn't known of anyone who had even thought about such an approach; that most people are so glad when treatment is over, they are not wanting to ask for anything more; that once your treatment is over, that is it, and you hope and pray for a good outcome.

When I saw Dr. Pegram in 2007, I asked him if "Herceptin maintainance" had ever been considered, and he said no, and that in my case, I had a year of herceptin and that should be enough; that trials were underway using fewer doses of herceptin.

I am hopeful that in the near (?) future a "tune-up" approach to staying NED will be in the works. Because cancer sometimes has a way of returning, perhaps tune-ups of some kind could keep that from happening.
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Blessings and Peace,
Barbara

DX Oct 02 @ age 52 Stage 2B Grade 3 Mastectomy
"at least" 4.5 cm IDC 1+node ER+61% /PR-
Assiciated Intraductual component with Comedo Necrosis
Her2+ FISH8.6 IHC 2+
5 1/2 CEF Arimidex
Celebrex 400mg daily for 13 months
Prophylactic mastectomy
Estradiol #: 13
PTEN positive, "late" Herceptin (26 months after chemo)
Oct 05: Actonel for osteopenia from Arimidex.
May 08: Replaced Actonel with Zometa . Taking every 6
months.

Accepting the gift of life, I give thanks for it and live it in fullness.

Last edited by Barbara2; 03-19-2010 at 11:44 AM.. Reason: sentence structure
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