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Old 07-06-2012, 02:47 PM   #10
CoolBreeze
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Join Date: Dec 2009
Posts: 562
Re: SRS and liver met

I also had a liver resection. It's a pretty rare surgery among breast cancer patients, so finding this many in one place is a treat! Joan is right, the oligo mets theory is becoming more accepted and they are starting to treat those of us with limited mets more aggressively.

I would not say - at all - that the liver surgery was an easy surgery. But, I'm glad did it. I had a more difficult time than others I think, since I got C-diff six weeks post-surgery. I nearly died from that and am still healing from it. (Surgery was in early October, I got septic with c-diff on Thanksgiving).

They removed all of the left lobe (which had two mets) and they found a spot in the right lobe with an unexpected met that they used microwave ablation on.

Before they do these surgeries, they do want to see response to chemo. You don't "let chemo finish the job" as somebody said, but you get some response and then they may do the surgical route. If they don't think it will do any good and you won't respond via chemo, they aren't going to take chances on you. In fact, if you get complete response they typically won't do the surgery. But there is still cancer cells there and you may be giving them time to move around.

I think you have to go to a major cancer center to get these newer treatments. Don't expect your home town oncologist to do them.

However, after my difficult experience, it appears that I'm NED. It's a cautious NED because although my UCSF surgeon thinks my PET scans show normal activity post-resection/ablation my oncologist isn't so sure. I've remained on Abraxane and herceptin. I may get to take an Abraxane break for a bit, which I'm looking forward to!

Good luck with your decision. I know it's not easy but you are lucky to live in a time where limited mets are treated aggressively and not just left to grow.
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08/17/09 Dx'd.
Multifocal/multicentric IDC, largest 3.4 cm, associated ADH, LCIS, DCIS
HER2+ ER+/PR- Grade 3, Node Negative

10/20/2009: Right mastectomy, reconstruction with TE
12/02/2009: Six rounds TCH, switched to Taxol halfway through due to neuropathy
03/31/2010: Finished chemo
05/01/2010: Began tamoxifen, the worst drug ever
11/18/2010: Reconstruction completed
12/02/2010: Finished herceptin
05/21/2011: Liver Mets. Quit Tamoxifen
06/22/2011: Navelbine/Zometa/Herceptin
10/03/2011: Liver Resection, left lobe. Microwave ablation, right lobe - going for cure!
11/26/2011: C-Diff Superbug Infection, "worst case doctor had seen in 20 years"
03/28/2012: Progression in ablated section of the liver - no more cure. Started Abraxane, continue herceptin/zometa
10/10/2012: Progression continues, started Halaven, along with herceptin and zometa.
01/15/2013: Progression continues, started Gemzar and Perjeta, an unusual combo, continuing with herceptin and zometa
03/13/2013: Quit Gemzar, body just won't handle it. Staying on herceptin, zometa and perjeta.
04/03/2013: CT shows 50% regression in tumor, so am starting back on Gemzar with dose reduction, staying with perjeta/herceptin/zometa. Can't argue with success!
05/09/2013: Discussing SBRT with Radiology due to inability of bone marrow to recover from chemo.
06/07/2013: Fiducial placement for SBRT
07/03/2013: Chemo discontinued, on Perjeta, Herceptin and Zometa alone
07/25/2013: SBRT (gamma knife) begins
08/01/2013: SBRT completed
08/15/2013: STABLE! continuing with Perjeta, Herceptin, Zometa
06/18/2014: ***** NED!!!!***** continuing with Perjeta, Herceptin, Zometa
01/29/2014: Still NED. continuing with Perjeta, Herceptin. Zometa lowered to every 3 months instead of monthly.
11/08/2015: Progression throughout abdomen and lungs. Started TDM-1, aka Kadcyla. Other meds discontinued. Remission was nice while it lasted.

5/27/18: Stable. Kadcyla put me right back in the barn. I have two teeny spots on my lungs that are metabolically inactive, and liver is clean.

I’m beating this MFer. I was 51 when this started and had two kids, 22 and 12. Now I’m 60. My oldest got married and trying to start s family. My youngesg graduates from Caltech this June. My stepdaughter gave me grandkids. Life is fantastic.
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