HER2 Support Group Forums - View Single Post - Tamoxifen, LHRH agonist, AI, oophorectomy??

Jackie07 · 02-11-2012, 05:02 PM

Hi Jane,

I had my hysterectomy/oophorectomy just before turning 51 because of the BRCA1-VUS component and family cancer history. I'd had chemopause since late 2003, so I did not experience much 'difference'. I do keep in mind that daily exercise is important because I've lost the many benefit of Estrogen.

To edit your treatment history in the Signature field - first go to User CP (on top of the Board-2nd from the left) From there, you will find 'Settings & Options' under 'Your Control Panel' Click on it and you will find 'Edit Signature' - that's where most of us save our treatment history.

I did a CYP2D6 test in 2010 because it was required by BCBS for me to continue taking Tamoxifen. There were some discussion on the Board at the time, and I believe the most recent research indicated that it's not as relavent as it was thought to be.

What is known (and the reason why my doctor put me back on Tamoxifen even after 5 years and after oophorectomy) is that continuing after 5 years results in a 4 % reduction in recurrence for Er+ BC suvivors.

02-11-2012, 05:02 PM	#4
Jackie07 Senior Member Join Date: Jan 2008 Location: "Love never fails." Posts: 5,808	Re: Tamoxifen, LHRH agonist, AI, oophorectomy?? Hi Jane, I had my hysterectomy/oophorectomy just before turning 51 because of the BRCA1-VUS component and family cancer history. I'd had chemopause since late 2003, so I did not experience much 'difference'. I do keep in mind that daily exercise is important because I've lost the many benefit of Estrogen. To edit your treatment history in the Signature field - first go to User CP (on top of the Board-2nd from the left) From there, you will find 'Settings & Options' under 'Your Control Panel' Click on it and you will find 'Edit Signature' - that's where most of us save our treatment history. I did a CYP2D6 test in 2010 because it was required by BCBS for me to continue taking Tamoxifen. There were some discussion on the Board at the time, and I believe the most recent research indicated that it's not as relavent as it was thought to be. What is known (and the reason why my doctor put me back on Tamoxifen even after 5 years and after oophorectomy) is that continuing after 5 years results in a 4 % reduction in recurrence for Er+ BC suvivors. __________________ Jackie07 http://www.kevinmd.com/blog/2011/06/doctors-letter-patient-newly-diagnosed-cancer.html http://www.asco.org/ASCOv2/MultiMedi...=114&trackID=2 NICU 4.4 LB Erythema Nodosum 85 Life-long Central Neurocytoma 4x5x6.5 cm 23 hrs 62090 semi-coma 10 d PT OT ST 30 d 3 Infertility tmts 99 > 3 u. fibroids > Pills CN 3 GKRS 52301 IDC 1.2 cm Her2 +++ ER 5% R. Lmptmy SLNB+1 71703 6 FEC 33 R Tamoxifen Recc IIB 2.5 cm Bi-L Mast 61407 2/9 nds PET 6 TCH Cellulitis - Lymphedema - compression sleeve & glove H w x 4 MUGA 51 D, J 49 M Diastasis recti Tamoxifen B. scan Irrtbl bowel 1'09 Colonoscopy 313 BRCA1 V1247I hptc hemangioma Vertigo GI - > yogurt hysterectomy/oophorectomy 011410 Exemestane 25 mg tab 102912 ~ 101016 stopped due to r. hip/l.thigh pain after long walk DEXA 1/13 1-2016 lesions in liver largest 9mm & 1.3 cm onco. says not cancer. 3-11 Appendectomy - visually O.K., a lot of puss. Final path result - not cancer. Start Vitamin D3 and Calcium supplement （600mg x2) 10-10 Stopped Exemestane due to r. hip/l.thigh pain OKed by Onco 11-08-2016 7-23-2018 9 mm groundglass nodule within the right lower lobe with indolent behavior. Due to possible adenocarcinoma, Recommend annual surveilence. 7-10-2019 CT to check lung nodule. 1-10-2020 8mm stable nodule on R Lung, two 6mm new ones on L Lung, a possible lymph node involvement in inter fissule. "I WANT TO BE AN OUTRAGEOUS OLD WOMAN WHO NEVER GETS CALLED AN OLD LADY. I WANT TO GET SHARP EDGED & EARTH COLORED, TILL I FADE AWAY FROM PURE JOY." Irene from Tampa Advocacy is a passion .. not a pastime - Joe Last edited by Jackie07; 02-11-2012 at 08:01 PM..