HER2 Support Group Forums - View Single Post - Brain Mets

Joan M · 02-14-2009, 06:56 AM

Courtney,

I can understand your fears. I had brain surgery in October to remove a 3 cm breast cancer metastatic lesion in my front left lobe followed by stereotatic radio therapy (five treatments).

I agree with Steph that you should consider local treatment and then add Tykerb if necessary.

My lesion was just a bit too large for effective treatment with SRT alone.

I'm still waiting on my three-month follow-up MRI with the radiation oncologist, which is scheduled for mid March, and will let you know the results.

However, I did have a brain MRI about two weeks ago, which was suggested by a neuro-oncologist I was supposed to meet with last Friday, but I was in the hospital and we never met. He asked me to do an MRI before the appointment. I'm trying to get those results now because my onc and I are trying to decide whether to add Tykerb.

Hang in there.

Joan

02-14-2009, 06:56 AM	#16
Joan M Senior Member Join Date: Oct 2007 Posts: 1,851	Courtney, I can understand your fears. I had brain surgery in October to remove a 3 cm breast cancer metastatic lesion in my front left lobe followed by stereotatic radio therapy (five treatments). I agree with Steph that you should consider local treatment and then add Tykerb if necessary. My lesion was just a bit too large for effective treatment with SRT alone. I'm still waiting on my three-month follow-up MRI with the radiation oncologist, which is scheduled for mid March, and will let you know the results. However, I did have a brain MRI about two weeks ago, which was suggested by a neuro-oncologist I was supposed to meet with last Friday, but I was in the hospital and we never met. He asked me to do an MRI before the appointment. I'm trying to get those results now because my onc and I are trying to decide whether to add Tykerb. Hang in there. Joan __________________ Diagnosed stage 2b in July 2003 (2.3 cm, HER2+, ER-/PR-, 7+ nodes). Treated with mastectomy (with immediate DIEP flap reconstruction), AC + T/Herceptin (off label). Cancer advanced to lung in Jan. 2007 (1 cm nodule). Started Herceptin every 3 weeks. Lung wedge resection April 2007. Cancer recurred in lung April 2008. RFA of lung in August 2008. 2nd annual brain MRI in Oct. 2008 discovered 2.6 cm cystic tumor in left frontal lobe. Craniotomy Oct. 2008 (ER-/PR-/HER2-) followed by targeted radiation (IMRT). Coughing up blood Feb. 2009. Thoractomy July 2009 to cut out fungal ball of common soil fungus (aspergillus) that grew in the RFA cavity (most likely inhaled while gardening). No cancer, only fungus. Removal of tiny melanoma from upper left arm, plus sentinel lymph node biopsy in Feb. 2016. Guardant Health liquid biopsy in Feb. 2016 showed mutations in 4 subtypes of TP53. Repeat of Guardant Health biopsy in Jana. 2021 showed 3 TP53 mutations, BRCA1 mutation and CHEK2 mutation. Invitae genetic testing showed negative for all of these. Living with MBC since 2007. Stopped Herceptin Hylecta (injection) treatment in March 2020. Recent 2021 annual CT of chest, abdomen and pelvis and annual brain MRI showed NED. Praying for NED forever!!