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Old 05-03-2007, 03:25 PM   #9
Lolly
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Join Date: Aug 2001
Location: Oregon
Posts: 1,756
Adriana; My onc started me on Herceptin/Navelbine in 2001 when I first recurred. Like you, this combo was very good for me. I've had a total of three recurrences, each time treated by adding Navelbine, for 6 months, to my maintenance Herceptin. However, each response was less "vigorous" and by the third recurrence I was "only" stable on the combo but we strung it out as long as possible before finally saying goodby to Navelbine last year when I started Xeloda. I think if you have a chance of getting another run with Navelbine, in my experience this tactic has worked well so far.
Good luck, and keep us posted.

<3 Lolly
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Sept.'99 - Dx.Stage IIIB, IDC ER/PR-, HER2+++ by IHC, confirmed '04 by FISH. Left MRM, AC x's 4, Taxol x's 4, 33 Rads, finishing Tx May 2000. Jan.'01 - local/regional recurrence, Stage IV. Herceptin/Navelbine weekly till NED August 2001, then maintenance Herceptin. Right Mast. April 2002. Local/Regional recurrence April '04, Herceptin plus/minus chemo until May '07. Gemzar added from Feb.'07-April '07; Tykerb/Abraxane until August '07, back on Herceptin plus Taxotere and Xeloda Sept. '07. Stopped T/X Nov. '07, stopped Herceptin Dec. '07, started Avastin/Taxol/Carboplatin Dec. '07. Progression in chest skin, stopped TAC March '03, started radiation.

Herceptin has served as the "Backbone" of my treatment strategy for over 6 years, giving me great quality of life. In 2005, I was privileged to participate in the University of Washington/Seattle HER2 Vaccine Trial.
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