HER2 Support Group Forums - View Single Post - Is there anyone who could not take AI's?

I had a shock last week when my doctor said that Aromasin was adversely affecting my liver. I thought that we had finally found an AI that I could tolerate. He said that I had tried all 3 and was now off AI's. It is just over a year since I started Femara and then switched to Arimidex. I am post-menopausal and 95% ER+. Is there anyone else who has faced this situation?

__________________
Mammo 6/2/09
left breast biopsy 6/12/09
Bad news 6/18/09!
7/17/09 lumpectomy
Stage 1- 0.5 cm IDC , DCIS 25%
HER2 +++, ER+95%, PR+10%
8/09 Muga Scan 65
8/19/09 beg. TCH 1Xwk. 12 wks.
last chemo 11/26/09
IMRT - 33 txs. 1/12/10 to 3/11/10
Herceptin 1X week for 1 yr. Ends 8/10
Femara 3X wk. started 1/13/10-too much pain in middle finger; switched to Arimidex 4/28/10 -permanently swollen, but no pain. Will continue for 5 yrs.
10/2/11 CT/PET scan due to elevated CA27.29 of 40.5.
Hot spot in irradiated area. Score goes down again to normal range. Subsequent blood tests go up and down until 2 tests in row at elevated levels of 42.5 & 45.7.
7/9/11 Intermittent vertigo. As a precaution contrast MRI to head. NED.
8/15/11 Erratic CA27.29 may be result of new auto immune disease, bullous pemphigoid (skin problem)
Off Arimidex for 6 wks. to see if trigger finger improves
Switched to Aromasin, 3X wk., but affected my liver.
On 2/23/12 taken off AI's.

02-26-2012, 09:53 PM	#1
Myra Lynn Senior Member Join Date: Jul 2009 Location: New York Posts: 106	Is there anyone who could not take AI's? I had a shock last week when my doctor said that Aromasin was adversely affecting my liver. I thought that we had finally found an AI that I could tolerate. He said that I had tried all 3 and was now off AI's. It is just over a year since I started Femara and then switched to Arimidex. I am post-menopausal and 95% ER+. Is there anyone else who has faced this situation? __________________ Mammo 6/2/09 left breast biopsy 6/12/09 Bad news 6/18/09! 7/17/09 lumpectomy Stage 1- 0.5 cm IDC , DCIS 25% HER2 +++, ER+95%, PR+10% 8/09 Muga Scan 65 8/19/09 beg. TCH 1Xwk. 12 wks. last chemo 11/26/09 IMRT - 33 txs. 1/12/10 to 3/11/10 Herceptin 1X week for 1 yr. Ends 8/10 Femara 3X wk. started 1/13/10-too much pain in middle finger; switched to Arimidex 4/28/10 -permanently swollen, but no pain. Will continue for 5 yrs. 10/2/11 CT/PET scan due to elevated CA27.29 of 40.5. Hot spot in irradiated area. Score goes down again to normal range. Subsequent blood tests go up and down until 2 tests in row at elevated levels of 42.5 & 45.7. 7/9/11 Intermittent vertigo. As a precaution contrast MRI to head. NED. 8/15/11 Erratic CA27.29 may be result of new auto immune disease, bullous pemphigoid (skin problem) Off Arimidex for 6 wks. to see if trigger finger improves Switched to Aromasin, 3X wk., but affected my liver. On 2/23/12 taken off AI's.