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I can not answer you question regarding being strongly Her2 and grade 1 cancer, as I don't know.
My tumor was "at least" 4.5cm, (Oct 2002) according to the information I received. The doctor never mentioned trying to shrink it first, but I think that might be because we really didn't know the size. It felt smaller than that, and the ultrasound was negative; the core of the tumor was smaller than that, but the "fingers" extended the tumor to 4.5cm. I, too, was Er+ which, yes, is a good thing.
I did get very sick with CEF chemo. I think the more current practice of 4 rounds of AC, followed by Taxol/herceptin would have been easier to tolerate. I was sickest with round 5 and 6 of chemo, which I wouldn't have had on the Taxol/herceptin plan.
I have a friend who did the AC, Taxol, then herceptin 5 years ago. She is a teacher, (mid 40's) and I don't think she ever missed any days due to illness, but she did admit there were a few times when she shouldn't have been working. It affects everyone differently. She is doing great and NED so far.
All the best to you. Barbara2
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