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Old 07-25-2006, 01:51 PM   #11
penelope
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Join Date: Jun 2006
Posts: 153
Ok this is what I have come to understand through my own research and the help of my sister who is a hematologist. She studies blood but is quite knowledgable in genetics.

Brca 1 and 2 are different. BRCA1 is usually estrogen negative
BRCA 2 is usually estrogen positive. This is not to say "always" but more often then not. It is unual to be BRCA1 or 2 and Her2+ as well. Again, sometimes it happens but rarely.
Her2+ is NOT genetic. I researched this at length with my sister as I am the third generation to have BC. So naturally we were worried when I was first diagnosed. I do not have any studies to cite here but I have read it several times. Now I probably carry a genetic predisposition to BC...clearly I am the third generation, but the her2+ apparently was sparodic.
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