Studies to watch:
Biological Therapy in Treating Women With Breast Cancer That Has Spread to the Liver
This study is ongoing, but not recruiting participants.
First Received: March 8, 2006 Last Updated: February 27, 2009
History of Changes
Sponsored by:
Mount Sinai School of Medicine
Information provided by: National Cancer Institute (NCI) ClinicalTrials.gov Identifier: NCT00301106
Purpose RATIONALE: Biological therapy using a gene-modified virus that can make interleukin-12 may help the body build an effective immune response to kill tumor cells.
PURPOSE: This phase I trial is studying the side effects and best dose of a gene-modified virus that can make interleukin-12 in treating women with breast cancer that has spread to the liver.
Condition Intervention Phase Breast Cancer
Metastatic Cancer
Biological: adenovirus-mediated human interleukin-12
Phase I
Interleukin-12 in Treating Patients With Metastatic or Recurrent Breast Cancer
This study is ongoing, but not recruiting participants.
Sponsors and Collaborators:
Cancer and Leukemia Group B
National Cancer Institute (NCI)
National Cancer Institute (NCI)
ClinicalTrials.gov Identifier:
NCT00004893
Purpose
RATIONALE: Interleukin-12 may kill tumor cells by stopping blood flow to the tumor and by stimulating a person's white blood cells to kill breast cancer cells.
PURPOSE: Randomized phase II trial to study the effectiveness of interleukin-12 in treating patients who have metastatic or recurrent breast cancer.
Breast Cancer
Biological: recombinant interleukin-12
Phase II