Randomized double-blind, placebo-controlled study of topical diclofenac in prevention of hand-foot syndrome in patients receiving capecitabine.
https://ascopubs.org/doi/abs/10.1200...16_suppl.12005
Conclusions: Topical diclofenac is effective in preventing all grades of HFS in patients receiving capecitabine. Diclofenac application was also associated with lesser dose reductions of capecitabine. This trial establishes topical diclofenac as the new standard of care to prevent capecitabine associated HFS.
Diclofenac: Cambia, Cataflam, Voltaren, Voltaren-XR, Zipsor, Zorvolex