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Old 12-15-2013, 02:53 AM   #11
donocco
Senior Member
 
Join Date: Oct 2013
Posts: 474
Re: Rads and the myth of chemo wiping out that "last stray cancer cell"

Apparently Metformin can selectively kill breast cancer stem cells whereas chemo drugs like Adriamycin cant. There is talk of combining Metformin with chemo . It apparently works by inhibiting the M-Tor pathway in a different manner than Affinitor whichis a direct M-Tor inhibitor. Metformin stimulates the activity of an enzyme called AMP-kinase and this results in a reduction of MTor activity. A dosage of 850mg twice daily of Metformin was suggested in a future clinical trial.

Paul
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