The first trial you have seen before I think the rest a new here.
Just in case you have lost sight of the omega threes and sixes
RB
http://www.ncbi.nlm.nih.gov/sites/en...ubmed_RVDocSum
"These findings reveal that the omega-3 PUFA ALA suppresses overexpression of HER2 oncogene at the transcriptional level, which, in turn, interacts synergistically with anti-HER2 trastuzumab- based immunotherapy. ii) Our results molecularly support a recent randomized double-blind placebo-controlled clinical trial suggesting that ALA may be a potential dietary alternative or adjunct to currently used drugs in the management of HER2-positive breast carcinomas. iii)
Considering our previous findings demonstrating the HER2 upregulatory actions of the omega-6 PUFA linolenic acid (LA; 18:2n-6) and the HER2 down-regulatory actions of the omega-3 PUFA docosahexaenoic acid (DHA; 22:6n-3) and of the omega-9 monounsaturated fatty acid oleic acid (OA; 18:1n-9), it is reasonable to suggest that a low omega-6/omega-3 PUFA ratio and elevated MUFA levels, the two prominent fat features of the Mediterranean diet, should be extremely efficient at blocking HER2 expression in breast cancer cells."
http://www.ncbi.nlm.nih.gov/sites/en...ubmed_RVDocSum
"our results indicate that (n-3) FA modify the lipid composition of membrane rafts and alter EGFR signaling in a way that d
ecreases the growth of breast tumors."
http://www.ncbi.nlm.nih.gov/sites/en...ubmed_RVDocSum
"Use of canola oil instead of corn oil in the diet may be a reasonable means to increase consumption of n-3 fatty acids with potential significance for
slowing growth of residual cancer cells in cancer survivors."
http://www.ncbi.nlm.nih.gov/sites/en...ubmed_RVDocSum
"In conclusion, we showed that erythrocyte compositions of specific fatty acids derived from fish intake, as biomarkers, a
re associated with lower risk of breast cancer, but further studies are needed to investigate mechanisms linked to the etiology. (c) 2007 Wiley-Liss, Inc."
http://www.ncbi.nlm.nih.gov/sites/en...ubmed_RVDocSum
"Since DHA influences the product of a major tumour suppressor gene, this finding may contribute to the observation that
high-fish consumption reduces the risk of breast cancer."
http://www.ncbi.nlm.nih.gov/sites/en...ubmed_RVDocSum
"Our results support the premise that DHA and genistein exert complementary actions whilst genistein is antagonistic to AA for controlling PGE(2) production as well as invasiveness of MDA-MB-231 cells in culture by modulating the level of NFkappaB expression."