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Old 10-29-2013, 11:00 AM   #3
'lizbeth
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Join Date: Apr 2008
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Re: targeting of erbB3 with MM-121/SAR256212 enhances paclitaxel

Here is the Merrimack Pharma's pipeline info for MM-121:

MM-121 (Signaling Inhibitor)

  • Indication:
  • Description:
  • Target
  • NSCLC, Breast Cancer, Ovarian Cancer
  • Monoclonal Antibody
  • ErbB3
MM-121/SAR256212 is a fully human monocolonal antibody that targets the HER3 receptor. Merrimack’s Network Biology approach identified HER3 as a critical tumorigenic node in several types of cancer.
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