Thread: What to do now?
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Old 12-05-2008, 01:55 PM   #3
chrisy
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Join Date: Sep 2005
Location: Central Coast, CA
Posts: 3,207
Hi Cheryl,
What you are hearing is correct, you have "done" it.

I'm not real clear on what stage your cancer was, but it sounds as if you have had all the treatment that would be considered "standard of care" as adjuvant treatment. You should specifically recheck the stat on recurrence - 50/50 seems incorrect, way too high particularly having no positive nodes prior to the surgery.

There is a statistic on adjuvant use of Herceptin which is that getting herceptin reduces your chance of recurrence by 50% compared to not getting Herceptin. So if your chance of recurrence before Herceptin would have been 20%, you reduce that to 10% if you get Herceptin. Maybe what you heard was a mixed up version of reducing your risk by 50%.

I think the recurrence stat was not clearly communicated to you.

At any rate, it is not standard of care to have any treatment beyond what you have had, although some ladies here who were diagnosed with Stage III and at high risk for recurrence have been able to extend their time on Herceptin and/or get Tykerb. Tykerb is not FDA approved for early stage bc, so this would be a challenge.

First, my suggestion is to get clarity on your staging and recurrence risk.
__________________
Chris in Scotts Valley
June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?"
9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++
10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response!
04/05 - 4/07 Herception every 3 wks, Continue NED
04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial
06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin
01/08 Progression in liver
02/08 Begin (TDM1) trial
08/08 NED! It's Working! Continue on TDM1
02/09 Continue NED
02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED
12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver
07/11 - 11/11 Herceptin/Xeloda -not working:(
12/11 Begin MM302 Phase I trial - bust:(
03/12 3rd times the charm? AKT trial

5/12 Scan shows reduction! 7/12 More reduction!!!!
8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!)
9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3
11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc
11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go.
2/13 Gemzar/Carbo/Herceptin - no go.
3/13 TACE procedure
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