HER2 Support Group Forums - View Single Post - vaccine results may not be as straight-forward as thought--a bit disconcerting!

'lizbeth · 08-22-2012, 03:09 PM

Lani,

I wasn't following the disconcerting part. I see now with the triple negative DCIS.

And you are right, I'm mixing apples and oranges again with dendritic and peptide vaccines. Still, it seems an important piece of research - even if it creates more questions than answers. And 18.5 ER+ to 40% ER- were NED as a result.

I do see only 50% effective with the Her2 eradication - which reminds me of Herceptin. I wonder if it would be the same 50% for whom Herceptin is not very effective, and I wonder if the reason is the same. Perhaps the other "weeds/phenotypes" are taking over?

I just found the phase I for the MUC1 breast vaccine trial for the triple negatives has 37 enrolled, but too early for results. Maybe someday in the future we will be see a treatment combination of more than 1 vaccine.

08-22-2012, 03:09 PM	#6
'lizbeth Senior Member Join Date: Apr 2008 Location: Sunny San Diego Posts: 2,214	Re: vaccine results may not be as straight-forward as thought--a bit disconcerting! Lani, I wasn't following the disconcerting part. I see now with the triple negative DCIS. And you are right, I'm mixing apples and oranges again with dendritic and peptide vaccines. Still, it seems an important piece of research - even if it creates more questions than answers. And 18.5 ER+ to 40% ER- were NED as a result. I do see only 50% effective with the Her2 eradication - which reminds me of Herceptin. I wonder if it would be the same 50% for whom Herceptin is not very effective, and I wonder if the reason is the same. Perhaps the other "weeds/phenotypes" are taking over? I just found the phase I for the MUC1 breast vaccine trial for the triple negatives has 37 enrolled, but too early for results. Maybe someday in the future we will be see a treatment combination of more than 1 vaccine. __________________ Diagnosed 2007 Stage IIb Invasive Ductal Carcinoma, Pagets, 3 of 15 positive nodes Traditional Treatment: Mastectomy and Axillary Node Dissection followed by Taxotere, 6 treatments and 1 year of Herceptin, no radiation Former Chemo Ninja "Takizi Zukuchiri" Additional treatments: GP2 vaccine, San Antonio Med Ctr Prescriptive Exercise for Cancer Patients ENERGY Study, UCSD La Jolla Reconstruction: TRAM flap, partial loss, Revision The content of my posts are meant for informational purposes only. The medical information is intended for general information only and should not be used in any way to diagnose, treat, cure, or prevent disease Last edited by 'lizbeth; 08-22-2012 at 03:19 PM.. Reason: Updated information.