Quote:
According to Yaffe, the concept of staggering drug treatments to achieve a maximum impact could be applied across a broad range of therapies. The team discovered similar boosts in tumor killing by pre-treating HER2-positive breast cancer cells with a HER2 inhibitor, followed by a DNA-damaging drug, and also observed good results with erlotinib and doxorubicin in some types of lung cancer.
Lee states:
"The drugs are going to be different for each cancer case, but the concept that time-staggered inhibition will be a strong determinant of efficacy has been universally true. It's just a matter of finding the right combinations."
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