HER2 Support Group Forums - View Single Post - for those with (or worried about) brain mets Avastin seems to cross the bbb

AlaskaAngel · 03-02-2007, 12:46 PM

Lani,

In demonstrating what does cross the BBB and what doesn't.... I'm puzzled... a drug could have a higher success rate without crossing the BBB if it acts upon something else in a way that then leads to a higher success rate.

I know it is a little gruesome to ask this common sense question... but what I don't understand is why proof of various drugs crossing the BBB isn't available by autopsy down the road?

A.A.

03-02-2007, 12:46 PM	#2
AlaskaAngel Senior Member Join Date: Sep 2005 Location: Alaska Posts: 2,018	Crossing the BBB Lani, In demonstrating what does cross the BBB and what doesn't.... I'm puzzled... a drug could have a higher success rate without crossing the BBB if it acts upon something else in a way that then leads to a higher success rate. I know it is a little gruesome to ask this common sense question... but what I don't understand is why proof of various drugs crossing the BBB isn't available by autopsy down the road? A.A.